Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Orange County offers clinical trials for a variety of conditions, including high blood pressure, heart disease, and skin disorders such as eczema, alopecia, and psoriasis. The city’s medical institutions are actively recruiting both healthy volunteers, as well as those with specific health needs to participate in studies that could improve treatments and outcomes for these, and many other widespread health issues.
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Results: 3,617
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
for
Squamous Cell Carcinoma of Head and Neck
Location: Fullerton CA, Los Angeles CA, Murrieta CA, La Jolla CA,
Sponsor: Janssen Research & Development, LLC
Sex: All
Age: 18+
Code: NCT07276399
Phase 3, Recruiting
A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
for
COVID-19, SARS-CoV-2 Infection
Location: Los Angeles CA, San Francisco CA
Sponsor: Kara Chew
Sex: All
Age: 40 - 64
Code: NCT06810934
Phase 1, Phase 2, Recruiting
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
for
Prostate Cancer
Location: Los Angeles CA, Santa Monica CA, Santa Barbara CA,
Sponsor: Novartis Pharmaceuticals
Sex: Male
Age: 18 - 70+
Code: NCT06780670
Phase 2, Phase 3, Recruiting
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
for
Carcinoma, Non-Small-Cell Lung
Location: Fullerton CA, Long Beach CA, Denver CO, Laredo TX,
Sponsor: Mirati Therapeutics Inc.
Sex: All
Age: 18+
Code: NCT06875310
Phase 3, Recruiting
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
for
Metastatic Solid Tumor, Recurrent Solid Tumor,
Location: Duarte CA, Los Angeles CA, La Jolla CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT06465069
Phase 1, Recruiting
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High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy
for
Diabetic Macular Edema (DME)
Location: Fullerton CA
Sponsor: Retina Consultants of Orange County
Sex: All
Age: 21+
Code: NCT06662994
Recruiting
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
for
Invasive Mold Infections
Location: Duarte CA, Los Angeles CA, Sacramento CA, Vancouver,
Sponsor: Basilea Pharmaceutica
Sex: All
Age: 18+
Code: NCT06925321
Phase 3, Recruiting
A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)
Location: Duarte CA, Los Angeles CA, Denver CO, Seattle WA,
Sponsor: Allotera Therapeutics
Sex: All
Age: 0+
Code: NCT06514794
Phase 2, Recruiting
A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma
for
Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma,
Location: Fullerton CA, Los Alamitos CA, Santa Monica CA,
Sponsor: TORL Biotherapeutics, LLC
Sex: All
Age: 18+
Code: NCT07439653
Phase 1, Phase 2, Recruiting
The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
for
Dementia
Location: Los Angeles CA
Sponsor: Healthy Minds Initiative
Sex: All
Age: 55 - 70+
Code: NCT06741865
Recruiting
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
for
Renal Cell Carcinoma
Location: Fullerton CA, Los Angeles CA, Omaha NE,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT07227402
Phase 3, Recruiting
A Study of Bleeding and Treatment in Participants With Von Willebrand Disease
for
Von Willebrand Disease (VWD),
Location: Los Angeles CA, Phoenix AZ, Portland OR, Seattle WA,
Sponsor: Hemab ApS
Sex: All
Age: 16+
Code: NCT06610201
Recruiting
Evidence-Based Quality Improvement to Reduce VA Primary Care Burnout
for
Burnout, Burnout Syndrome
Location: Los Angeles CA
Sponsor: VA Greater Los Angeles Healthcare System
Sex: All
Age: 0+
Code: NCT07031245
Recruiting
A Clinical Registry to Demonstrate the Safety and Performance of Teleflex Vascular Access Devices
for
Vascular Access Device
Location: Loma Linda CA, Huntsville AL, Boston MA
Sponsor: Teleflex
Sex: All
Age: 0+
Code: NCT06604039
Recruiting
Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
for
Melanoma Stage IV, Solid Tumor
Location: Fullerton CA, Los Angeles CA, Bakersfield CA,
Sponsor: Georgiamune Inc
Sex: All
Age: 18+
Code: NCT06425926
Phase 1, Phase 2, Recruiting
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
for
Follicular Lymphoma
Location: Duarte CA, San Francisco CA, Austin TX, Tyler TX,
Sponsor: Celgene
Sex: All
Age: 18+
Code: NCT06911502
Phase 3, Recruiting
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
for
Age Related Cataracts
Location: Torrance CA, Gainesville GA, Cape Coral FL
Sponsor: Argus Research Center, Inc.
Sex: All
Age: 0+
Code: NCT07006428
Recruiting
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
for
Schizophrenia
Location: La Habra CA, Cerritos CA, Pico Rivera CA, Chino CA,
Sponsor: Neurocrine Biosciences
Sex: All
Age: 18 - 65
Code: NCT07114874
Phase 3, Recruiting
A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function
for
Semen Quality
Location: Pomona CA, North Hollywood CA, Middleburg Heights OH,
Sponsor: ReproNovo Aps
Sex: Male
Age: 18 - 49
Code: NCT06993155
Phase 2, Recruiting
Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma