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Paid Clinical Trials Orange County

Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for
Bone Pain, Metastatic Malignant Neoplasm in the Bone,
Location: Duarte CA, Los Angeles CA, Minneapolis MN, Atlanta GA,
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03858205

Recruiting
Active & Responsive

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for
Acute Myeloid Leukemia
Location: Duarte CA, Phoenix AZ, Stanford CA, Salt Lake City UT,
Sponsor: Norman J. Lacayo

Sex: All

Age: 0 - 21

Code: NCT05101551

Phase1, Recruiting
Active & Responsive

Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

for
Non-Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Refractory,
Location: Duarte CA, Denver CO, Aurora CO, Austin TX,
Sponsor: Marker Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05798897

Phase1, Recruiting
Active & Responsive

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for
CLL/SLL
Location: Duarte CA, Seattle WA, Cleveland OH, Canton OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04215809

Phase1, Recruiting
Active & ResponsiveNew

A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

for
Relapsed or Refractory Multiple Myeloma
Location: Duarte CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07681596

Phase1, Phase2, Recruiting

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Active & Responsive

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06059391

Phase2, Recruiting
Active & Responsive

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase1, Recruiting
Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Duarte CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase3, Recruiting
Active & Responsive

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

for
Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm,
Location: Duarte CA, Los Angeles CA, Ann Arbor MI
Sponsor: City of Hope Medical Center

Sex: All

Age: 4 - 25

Code: NCT04510051

Phase1, Recruiting
Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Torrance CA, Los Angeles CA, Beverly Hills CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase3, Recruiting
Active & Responsive

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

for
Episodic Migraine
Location: Torrance CA, Los Angeles CA, Thousand Oaks CA,
Sponsor: Merz Therapeutics GmbH

Sex: All

Age: 18+

Code: NCT07018700

Phase3, Recruiting
Active & Responsive

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for
Solid Tumor
Location: Duarte CA, La Jolla CA, Palo Alto CA,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06384807

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for
Rheumatoid Arthritis
Location: Upland CA, Los Angeles CA, La Jolla CA, Peoria AZ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07137598

Phase2, Recruiting
Active & Responsive

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

for
Obstructive Sleep Apnea
Location: Rolling Hills Estates CA, Northridge CA, Bellevue WA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07226765

Phase3, Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Los Angeles CA, Rancho Mirage CA, Las Vegas NV,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase3, Recruiting
Active & Responsive

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for
Inherited Retinal Degeneration, Retinitis Pigmentosa
Location: Los Angeles CA, San Francisco CA, Salt Lake City UT,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 4+

Code: NCT05589714

Recruiting
Active & Responsive

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Los Angeles CA, Redwood City CA, San Francisco CA,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05338697

Recruiting
Active & Responsive

Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

for
Low Back Pain
Location: Los Angeles CA, Beverly Hills CA, La Jolla CA,
Sponsor: Aclarion

Sex: All

Age: 18 - 70

Code: NCT06661850

Recruiting
Active & Responsive

The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for
Intracranial Aneurysm
Location: Los Angeles CA, Salt Lake City UT, Englewood CO,
Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All

Age: 18 - 70+

Code: NCT02998229

Recruiting