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Paid Clinical Trials Orange County

Discover 3,614 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

for
Recurrent Astrocytoma, IDH-Mutant, Grade 4,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07544992

Phase 1, Recruiting
Active & Responsive

CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS

for
HIV-1
Location: Duarte CA, San Diego CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06252402

Early Phase 1, Recruiting
Active & Responsive

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for
PIK3CA Mutation, HER2- Negative Breast Cancer,
Location: Duarte CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06982521

Phase 3, Recruiting
Active & Responsive

Pancreatic Cancer Detection Consortium

for
Pancreatic Cancer, Pancreatic Carcinoma,
Location: Monrovia CA, Phoenix AZ, Tacoma WA, Peoria IL,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06388967

Recruiting
Active & Responsive

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06059391

Phase 2, Recruiting

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Active & Responsive

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

for
Metastatic Lung Non-Small Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07619599

Phase 1, Recruiting
Active & Responsive

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT07020533

Phase 1, Recruiting
Active & Responsive

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

for
Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm,
Location: Duarte CA, Los Angeles CA, Ann Arbor MI
Sponsor: City of Hope Medical Center

Sex: All

Age: 4 - 25

Code: NCT04510051

Phase 1, Recruiting
Active & Responsive

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Torrance CA, Los Angeles CA, Beverly Hills CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05929768

Phase 3, Recruiting
Active & Responsive

A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for
Solid Tumor
Location: Duarte CA, La Jolla CA, Palo Alto CA,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT06384807

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for
Rheumatoid Arthritis
Location: Upland CA, Los Angeles CA, La Jolla CA, Avondale AZ,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07137598

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

for
Atopic Dermatitis, Atopic Dermatitis Eczema, Eczema
Location: Los Angeles CA, Lancaster CA, Portland OR, Burien WA,
Sponsor: Inmagene LLC

Sex: All

Age: 18 - 70+

Code: NCT07037901

Phase 2, Recruiting
Active & Responsive

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Location: Los Angeles CA, Rancho Mirage CA, Las Vegas NV,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07198074

Phase 3, Recruiting
Active & Responsive

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for
Inherited Retinal Degeneration, Retinitis Pigmentosa
Location: Los Angeles CA, San Francisco CA, Salt Lake City UT,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 4+

Code: NCT05589714

Recruiting
Active & Responsive

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for
Treatment Resistant Depression
Location: Los Angeles CA, Sacramento CA, Salt Lake City UT,
Sponsor: Abbott Medical Devices

Sex: All

Age: 22 - 70

Code: NCT06423430

Recruiting
Active & Responsive

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for
Type 1 Diabetes Mellitus With Hypoglycemia
Location: Los Angeles CA, Escondido CA, Las Vegas NV,
Sponsor: Zucara Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT05762107

Phase 2, Recruiting
Active & Responsive

Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

for
Low Back Pain
Location: Los Angeles CA, Beverly Hills CA, La Jolla CA,
Sponsor: Aclarion

Sex: All

Age: 18 - 70

Code: NCT06661850

Recruiting
Active & Responsive

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Los Angeles CA, Redwood City CA, San Francisco CA,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05338697

Recruiting
Active & Responsive

The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for
Intracranial Aneurysm
Location: Los Angeles CA, Salt Lake City UT, Englewood CO,
Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All

Age: 18 - 70+

Code: NCT02998229

Recruiting
Active & Responsive

Multi-Site Trial of Tirzepatide for Smoking Cessation

for
Smoking Cessation, Smoking Behaviors
Location: Los Angeles CA, Aurora CO, Chicago IL, New Haven CT
Sponsor: University of Southern California

Sex: All

Age: 21 - 65

Code: NCT07602699

Phase 2, Recruiting