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Paid Clinical Trials Orange County

Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Disorder
Location: Orange CA, Toronto, Oceanside CA, New Haven CT,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT07196501

Phase 3, Recruiting

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for
Asthma
Location: Orange CA, Westminster CA, Mission Viejo CA,
Sponsor: AstraZeneca

Sex: All

Age: 12 - 17

Code: NCT06307665

Phase 3, Recruiting

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

for
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder,
Location: Orange CA, Long Beach CA, Chino CA, Redlands CA,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT07105111

Recruiting

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Episode (MDE), Major Depressive Disorder (MDD),
Location: Orange CA, Buena Park CA, Chino CA, San Diego CA,
Sponsor: Tonix Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07621237

Phase 2, Recruiting

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

for
Hypertension (HTN)
Location: Garden Grove CA, Los Angeles CA, Edmond OK,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07543120

Phase 2, Recruiting

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Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for
Endometrial Cancer, Malignant Solid Tumour
Location: Orange CA, La Jolla CA, Albuquerque NM, Eugene OR,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT07044336

Phase 3, Recruiting

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

for
Psychosis Associated With Alzheimer's Disease
Location: Orange CA, Anaheim CA, Long Beach CA, Murrieta CA,
Sponsor: MapLight Therapeutics

Sex: All

Age: 55 - 70+

Code: NCT06887192

Phase 2, Recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for
Endometrial Cancer
Location: Orange CA, Irvine CA, Solvang CA, Walnut Creek CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06952504

Phase 3, Recruiting

Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers

for
Uric Acid Stones
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70+

Code: NCT06335537

Phase 1, Recruiting

Diagnosing Epilepsy To EffeCT Change

for
Epilepsy, Epilepsy (Treatment Refractory)
Location: Irvine CA, San Diego CA, Phoenix AZ, Palo Alto CA,
Sponsor: Epiminder America, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07110337

Recruiting

Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Location: Orange CA, Houston TX, Fairfax VA, Baltimore MD,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT04686305

Phase 1, Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

for
Advanced Metastatic Castration Resistant Prostate Cancer
Location: Orange CA, Newport Beach CA, Scottsdale AZ, Spokane WA,
Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: Male

Age: 18+

Code: NCT06609005

Phase 1, Phase 2, Recruiting

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

for
Hepatocellular Carcinoma (HCC)
Location: Orange CA, Phoenix AZ, Seattle WA, Omaha NE, Houston TX,
Sponsor: RayzeBio, Inc.

Sex: All

Age: 18+

Code: NCT06726161

Phase 1, Phase 2, Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for
Pulmonary Embolism
Location: Orange CA, Long Beach CA, Los Angeles CA, San Diego CA,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT04798261

Recruiting

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Irvine CA, Los Angeles CA, Seattle WA, Charlotte NC,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06697197

Phase 1, Phase 2, Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer
Location: Orange CA, Los Alamitos CA, Los Angeles CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06350097

Phase 3, Recruiting

Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder

for
Generalized Anxiety Disorder
Location: Orange CA, Glendale CA, Redlands CA, Oceanside CA,
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 0+

Code: NCT06480383

Phase 2, Recruiting

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for
Chronic Graft-Versus-Host Disease (cGVHD)
Location: Orange CA, Duarte CA, Los Angeles CA, Salt Lake City UT,
Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All

Age: 18+

Code: NCT06619561

Phase 2, Recruiting

Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

for
Skin Burn Multiple
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 0+

Code: NCT01166893

Recruiting

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for
Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer,
Location: Orange CA, Stanford CA, Sacramento CA, Aurora CO,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06128551

Phase 1, Phase 2, Recruiting