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Paid Clinical Trials Orange County

Discover 3,617 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung
Location: Orange CA, Los Angeles CA, Oceanside CA, San Diego CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06890598

Phase 3, Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Location: Orange CA, Newport Beach CA, Glendale AZ, Boulder CO,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06765109

Phase 3, Recruiting

Shorter Versus Extended Course of Antibiotic Therapy for Necrotizing Soft Tissue Infections

for
Necrotizing Soft Tissue Infection
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06002607

Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for
Acute Respiratory Distress Syndrome (ARDS), ARDS,
Location: Orange CA, Long Beach CA, Fresno CA, Stanford CA,
Sponsor: PPD Development, LP

Sex: All

Age: 18+

Code: NCT06701656

Phase 2, Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: Orange CA, Irvine CA, Duarte CA, Los Angeles CA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase 1, Recruiting

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for
Chronic Kidney Disease and Hypertension
Location: Fullerton CA, Los Alamitos CA, Beverly Hills CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06742723

Phase 3, Recruiting

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
Location: Orange CA, Newport Beach CA, Los Angeles CA,
Sponsor: United Therapeutics

Sex: All

Age: 18+

Code: NCT05943535

Phase 3, Recruiting

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for
Intracerebral Hemorrhage, Atrial Fibrillation
Location: Orange CA, Fullerton CA, Los Alamitos CA, Whittier CA,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT03907046

Phase 3, Recruiting

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for
Acute Respiratory Distress Syndrome (ARDS), ARDS,
Location: Orange CA, Long Beach CA, Fresno CA, Stanford CA,
Sponsor: PPD Development, LP

Sex: All

Age: 18+

Code: NCT06701669

Phase 2, Recruiting

Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

for
Obesity
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18 - 70

Code: NCT05975580

Phase 4, Recruiting

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

for
Urothelial Carcinoma
Location: Orange CA, Irvine CA, Anaheim CA, Newport Beach CA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT04879329

Phase 2, Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for
Metastatic Castration-resistant Prostate Cancer (mCRPC),
Location: Orange CA, Irvine CA, Riverside CA, Los Angeles CA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06136650

Phase 3, Recruiting

Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

for
Surgery, Anesthesia, Local, Fasting
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT05819801

Recruiting

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for
IC-MPGN
Location: Orange CA, Los Angeles CA, Sylmar CA, San Francisco CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 60

Code: NCT05755386

Phase 3, Recruiting

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

for
Primary Mitochondrial Disease
Location: Orange CA, San Diego CA, Aurora CO, Houston TX,
Sponsor: Pharming Technologies B.V.

Sex: All

Age: 18+

Code: NCT05650229

Phase 2, Recruiting

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for
Prostate Cancer
Location: Orange CA, Santa Barbara CA, Palo Alto CA, Tucson AZ,
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18 - 70+

Code: NCT06855277

Phase 3, Recruiting

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for
Myopia, Juvenile Myopia, Myopia Progression
Location: Santa Ana CA, San Diego CA, Oakland CA,
Sponsor: SightGlass Vision, Inc.

Sex: All

Age: 6 - 8

Code: NCT06034327

Recruiting

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for
Relapsing Multiple Sclerosis, Multiple Sclerosis
Location: Orange CA, Newport Beach CA, West Hollywood CA,
Sponsor: TG Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06433752

Recruiting

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

for
Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis
Location: Orange CA, Riverside CA, Murrieta CA, Sherman Oaks CA,
Sponsor: Lighthouse Pharmaceuticals, Inc.

Sex: All

Age: 55 - 70+

Code: NCT06847321

Phase 2, Recruiting

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

for
Major Depressive Disorder
Location: Orange CA, Anaheim CA, Long Beach CA, West Covina CA,
Sponsor: Autobahn Therapeutics, Inc.

Sex: All

Age: 18 - 65

Code: NCT06633016

Phase 2, Recruiting