Paid Clinical Trials Cambridge

Discover 2,948 paid clinical trials in Cambridge, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 2,948

A Study of EP0031 in Patients With Advanced RET-altered MalignanciesA Study of EP0031 in Patients With Advanced RET-altered Malignancies

Recruiting

PHASE1

PHASE2

Sponsor:

Ellipses Pharma

Location:

Boston MA, New York NY, Philadelphia PA, Washington DCshow 12 more

Code:

NCT05443126

Conditions

Advanced Solid Tumor

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

EP0031

TReatment of ADC-Refractory Breast CancEr with Dato-DXd or T-DXd: TRADE DXdTReatment of ADC-Refractory Breast CancEr with Dato-DXd or T-DXd: TRADE DXd

Recruiting

PHASE2

Sponsor:

Ana C Garrido-Castro, MD

Location:

Boston MA

Code:

NCT06533826

Conditions

Breast Cancer

HER2-low Breast Cancer

Metastatic Breast Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Trastuzumab Deruxtecan

Datopotamab Deruxtecan

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative ColitisA Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

Recruiting

PHASE2

Sponsor:

Pfizer

Location:

Boston MA, Lebanon NH, Rochester NY, Cleveland OHshow 14 more

Code:

NCT05287126

Conditions

Ulcerative Colitis

Eligibility Criteria

Sex: All

Age: 12 - 17

Healthy Volunteers: Not accepted

Interventions

Etrasimod

A Trial Comparing Unrelated Donor BMT with IST for Pediatric and Young Adult Patients with Severe Aplastic Anemia (TransIT, BMT CTN 2202)A Trial Comparing Unrelated Donor BMT with IST for Pediatric and Young Adult Patients with Severe Aplastic Anemia (TransIT, BMT CTN 2202)

Recruiting

PHASE3

Sponsor:

Boston Children's Hospital

Location:

Boston MA, Scarborough ME, New Haven CT, New Hyde Park NYshow 43 more

Code:

NCT05600426

Conditions

Severe Aplastic Anemia

Eligibility Criteria

Sex: All

Age: 0 - 25

Healthy Volunteers: Not accepted

Interventions

cyclosporine

Matched Unrelated Donor Hematopoetic Stem Cell Transplant

horse anti-thymocyte globulin (ATG)

rabbit anti-thymocyte globulin (ATG)

Methotrexate

Phase 1/2 Study to Evaluate Vosilasarm (EP0062) as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast CancerPhase 1/2 Study to Evaluate Vosilasarm (EP0062) as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Recruiting

PHASE1

PHASE2

Sponsor:

Ellipses Pharma

Location:

Boston MA, New Haven CT, Fairfax VA, Detroit MIshow 3 more

Code:

NCT05573126

Conditions

Hormone Receptor-positive Breast Cancer

Hormone Receptor Positive HER-2 Negative Breast Cancer

Metastatic Breast Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Vosilasarm

Elacestrant

Everolimus

ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain StimulatorsON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators

Recruiting

Sponsor:

Massachusetts General Hospital

Location:

Charlestown MA, Boston MA

Code:

NCT01590862

Conditions

Obsessive Compulsive Disorder

Major Depressive Disorder

Epilepsy

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

Deep Brain Stimulator

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)

Recruiting

PHASE3

Sponsor:

UCB Biopharma SRL

Location:

Boston MA, Baltimore MD, Washington DC, Cleveland OHshow 10 more

Code:

NCT05063162

Conditions

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Rozanolixizumab

Placebo

Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy AssessmentCardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Recruiting

Sponsor:

XSpline S.p.A.

Location:

Boston MA, Durham NC, Chicago IL

Code:

NCT05327062

Conditions

Cardiac Resynchronization Therapy

Chronic Heart Failure

Left Bundle-Branch Block

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

Recruiting

PHASE3

Sponsor:

Chimerix

Location:

Boston MA, Albany NY, Fairfield CT, New York NYshow 53 more

Code:

NCT05580562

Conditions

H3 K27M

Glioma

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Dordaviprone (ONC201)

Dordaviprone (ONC201) + Placebo

Placebo

Circadian Influence on Prolonged Exposure Therapy for PTSDCircadian Influence on Prolonged Exposure Therapy for PTSD

Recruiting

Sponsor:

Massachusetts General Hospital

Location:

Boston MA

Code:

NCT05453162

Conditions

PTSD

Eligibility Criteria

Sex: All

Age: 25 - 45

Healthy Volunteers: Not accepted

Interventions

Prolonged Exposure Therapy for Posttraumatic Stress Disorder