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Paid Clinical Trials Cambridge

Discover 3,059 paid clinical trials in Cambridge, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial

for
Critical Illness, Post Operative Complication, Thoracic Surgery
Location: Boston MA
Sponsor: Wandercraft

Sex: All

Age: 18+

Code: NCT07220733

Phase 1, Phase 2, Recruiting

Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

for
Schizophrenia
Location: Boston MA, Gaithersburg MD, Chicago IL, Decatur GA,
Sponsor: Reviva Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT05184335

Phase 3, Recruiting

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for
Acute Migraine
Location: Boston MA, Waltham MA, Waterbury CT, Commack NY,
Sponsor: Kallyope Inc.

Sex: All

Age: 18+

Code: NCT07674654

Phase 3, Recruiting

A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)

for
Inflammatory Arthritis,
Location: Newton MA, New York NY, Charleston SC
Sponsor: Smith & Nephew, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07199738

Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection

for
Coronavirus Infection, Severe Acute Respiratory Infection,
Location: Boston MA, Bronx NY, New York NY, Newark NJ,
Sponsor: Biomed Industries, Inc.

Sex: All

Age: 18 - 70+

Code: NCT04452565

Phase 2, Phase 3, Recruiting

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Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

for
Metastatic Prostate Cancer
Location: Boston MA, Providence RI, New York NY, Detroit MI,
Sponsor: AstraZeneca

Sex: Male

Age: 18 - 70+

Code: NCT07181161

Phase 1, Phase 2, Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Cleveland OH,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase 1, Recruiting

Study of Novel Therapeutics for Acute Remedy of Colitis

for
Ulcerative Colitis, Ulcerative Colitis Chronic Moderate,
Location: Chestnut Hill MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 70+

Code: NCT06420492

Phase 2, Recruiting

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for
Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Location: Boston MA, Philadelphia PA, Pittsburgh PA, Cleveland OH,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT07140900

Phase 1, Recruiting

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for
Sepsis, Acute Kidney Injury
Location: Boston MA, The Bronx NY, Montreal, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT07215702

Phase 2, Recruiting

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for
Clostridioides Difficile Infection
Location: Boston MA, Hamden CT, The Bronx NY, Union City NJ,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07285213

Phase 2, Recruiting

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

for
COPD (Chronic Obstructive Pulmonary Disease)
Location: Worcester MA
Sponsor: University of Massachusetts, Worcester

Sex: All

Age: 40+

Code: NCT07072039

Recruiting

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

for
Ultomiris-exposed Pregnant/ Postpartum, Pregnancy,
Location: Boston MA
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: Female

Age: 0+

Code: NCT06312644

Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

for
Asthma
Location: Boston MA, Hawthorne NY, Staten Island NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 11

Code: NCT06023589

Phase 3, Recruiting

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

for
Proteinuric Renal Disease, Proteinuric Kidney Disease,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18+

Code: NCT07224776

Phase 1, Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Boston MA, Providence RI, Montreal, Fairfax VA, Toronto,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase 1, Phase 2, Recruiting

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for
Rhabdomyosarcoma
Location: Boston MA, Worcester MA, Providence RI, Sanford ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 50

Code: NCT07466316

Phase 3, Recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for
Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR, ATTR-Mixed,
Location: Boston MA, New Haven CT, Manhasset NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06465810

Recruiting

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

for
Neuromyelitis Optica Spectrum Disorder, NMOSD, AQP4+ NMOSD
Location: Boston MA, Washington D.C. DC, Columbus OH,
Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05966467

Recruiting

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for
Relapsed/Refractory Multiple Myeloma
Location: Boston MA, Stony Brook NY, New York NY,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05850234

Phase 1, Phase 2, Recruiting