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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for
Metastatic Breast Cancer
Location: Durham NC, Chattanooga TN, Nashville TN, Germantown TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT03424005

Phase1, Phase2, Recruiting
FeaturedActive & Responsive

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for
Geographic Atrophy
Location: Durham NC, Lynchburg VA, Baltimore MD, Philadelphia PA,
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT05626114

Phase2, Recruiting
FeaturedActive & Responsive

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

for
Juvenile Psoriatic Arthritis
Location: Chapel Hill NC, Washington D.C. DC, Cleveland OH,
Sponsor: AbbVie

Sex: All

Age: 5 - 17

Code: NCT06100744

Phase3, Recruiting
Featured

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

for
Colorectal Cancer
Location: Durham NC, Blacksburg VA, Cincinnati OH, Newnan GA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07525206

Phase3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Durham NC, Winston-Salem NC, Charlotte NC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase3, Recruiting

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Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Durham NC, Raleigh NC, Fayetteville NC,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Durham NC, Fayetteville NC, Winston-Salem NC,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Durham NC, Richmond VA, Charlottesville VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase3, Recruiting
Featured

Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or Qulipta (Atogepant) During Pregnancy

for
Migraine
Location: Durham NC, Ottawa
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT05158894

Recruiting
Featured

Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications

for
Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment,
Location: Morrisville NC
Sponsor: AbbVie

Sex: Female

Age: 0+

Code: NCT04846959

Recruiting
Featured

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Chapel Hill NC, Winston-Salem NC, Fairfax VA, Newark DE,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05650632

Phase1, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Chapel Hill NC, Winston-Salem NC, Charlotte NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase1, Phase2, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for
Atherosclerosis
Location: Chapel Hill NC, Pittsburgh PA, North Massapequa NY,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07448038

Phase2, Recruiting
Featured

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

for
Non-cystic Fibrosis Bronchiectasis,
Location: Chapel Hill NC, Pittsburgh PA, Birmingham AL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT06603246

Phase1, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Chapel Hill NC, Fairfax VA, Marietta GA, Cincinnati OH,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Chapel Hill NC, Winston-Salem NC, Greenville NC,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
FeaturedNew

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

for
Obesity, Overweight
Location: Danville VA, Greensboro NC, Monroe NC, New Bern NC,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07752979

Phase2, Recruiting
Featured

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

for
Episodic Migraine
Location: Greensboro NC, Franklin VA, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05711394

Phase3, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Greensboro NC, Richmond VA, Fairfax VA, Summerville SC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for
Alzheimers Disease
Location: Greensboro NC, Richmond VA, Knoxville TN, Decatur GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07169578

Phase3, Recruiting