Paid Clinical Trials North Carolina

Discover 2,419 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Results: 2,419

ImmunotherapyImmunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Recruiting

PHASE1

Sponsor:

Sabine Mueller, MD, PhD

Location:

Durham NC, Washington DC, Baltimore MD, Birmingham ALshow 9 more

Code:

NCT04323046

Conditions

Glioblastoma

Malignant Glioma

Recurrent Glioblastoma

Recurrent Malignant Glioma

Recurrent Grade III Glioma

Eligibility Criteria

Sex: All

Age: 6 - 25

Healthy Volunteers: Not accepted

Interventions

Nivolumab

Quality-of-Life Assessment

Questionnaire Administration

TebapivatA Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Recruiting

PHASE2

Sponsor:

Agios Pharmaceuticals, Inc.

Location:

Durham NC, Jacksonville FL, Long Island City NY, New Haven CTshow 5 more

Code:

NCT05490446

Conditions

Myelodysplastic Syndromes

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tebapivat

Observational StudyRegistry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction

Recruiting

Sponsor:

Axogen Corporation

Location:

Durham NC, Charlotte NC, Richmond VA, Mount Pleasant SCshow 33 more

Code:

NCT01526681

Conditions

Peripheral Nerve Injuries

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Processed Human Nerve Graft

Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc.

Autogenous Nerve Graft

Nerve Tube Conduit

Autologous Breast Reconstruction with Neurotization

ASP2138 with Cancer TreatmentsA Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting

PHASE1

Sponsor:

Astellas Pharma Global Development, Inc.

Location:

Winston-Salem NC, Durham NC, New Brunswick NJ, New York NYshow 7 more

Code:

NCT05365581

Conditions

Gastric Adenocarcinoma

Gastroesophageal Junction (GEJ) Adenocarcinoma

Pancreatic Adenocarcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

ASP2138

Pembrolizumab

Oxaliplatin

Leucovorin

Fluorouracil

Remibrutinib vs. TeriflunomideEfficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Recruiting

PHASE3

Sponsor:

Novartis Pharmaceuticals

Location:

Chapel Hill NC, Charlotte NC, Indian Land SC, Greenville SCshow 59 more

Code:

NCT05156281

Conditions

Relapsing Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Remibrutinib

Teriflunomide

Nexel Total ElbowClinical Outcomes Study of the Nexel Total Elbow

Recruiting

Sponsor:

Zimmer Biomet

Location:

Charlotte NC, Philadelphia PA, Germantown TN, Golden CO

Code:

NCT02469662

Conditions

Elbow Joint Destruction

Post-traumatic Lesions

Ankylosed Joints

Advanced Rheumatoid Arthritis

Joint Instability or Loss of Motion

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Nexel Total Elbow

P-CD19CD20-ALLO1P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Recruiting

PHASE1

Sponsor:

Poseida Therapeutics, Inc.

Location:

Chapel Hill NC, Greenville SC, Cincinnati OH, Nashville TNshow 5 more

Code:

NCT06014762

Conditions

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

High-grade B-cell Lymphoma

Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Transformed Follicular Lymphoma (tFL)

Follicular Lymphoma Grade 3B

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

P-CD19CD20-ALLO1

Rimiducid

LY3556050A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

Recruiting

PHASE2

Sponsor:

Eli Lilly and Company

Location:

Hickory NC, Morehead City NC, Knoxville TN, Lexington KYshow 29 more

Code:

NCT06074562

Conditions

Diabetic Peripheral Neuropathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

LY3556050

Placebo

Crenolanib vs. MidostaurinStudy of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML

Recruiting

PHASE3

Sponsor:

Arog Pharmaceuticals, Inc.

Location:

Winston-Salem NC, Chapel Hill NC, Charlottesville VA, New Brunswick NJshow 17 more

Code:

NCT03258931

Conditions

Newly Diagnosed FLT3 Mutated AML

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Crenolanib

Midostaurin

Cytarabine

Duanorubicin

Efgartigimod PH20A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR)

Recruiting

PHASE2

Sponsor:

argenx

Location:

Durham NC, Richmond VA, Columbus OH, Birmingham ALshow 2 more

Code:

NCT06503731

Conditions

Antibody-mediated Rejection

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Efgartigimod PH20 SC - prefilled syringe

Placebo PH20 SC - prefilled syringe

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