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Paid Clinical Trials Dayton

Discover 1,190 paid clinical trials in Dayton, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

for
Epileptic Encephalopathy, SCN2A Encephalopathy
Location: Cincinnati OH, Chicago IL, Memphis TN, Philadelphia PA,
Sponsor: Praxis Precision Medicines

Sex: All

Age: 0 - 18

Code: NCT07019922

Phase 3, Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for
Systemic Lupus Erythematosus
Location: Cincinnati OH, Columbus OH, Cleveland OH, Chicago IL,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 17

Code: NCT05835310

Phase 3, Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

for
Hyperkalaemia
Location: Cincinnati OH, Baltimore MD, Columbia SC, Birmingham AL,
Sponsor: AstraZeneca

Sex: All

Age: 0 - 18

Code: NCT03813407

Phase 3, Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for
Breast Cancer
Location: Cincinnati OH, Cleveland OH, Detroit MI, Chicago IL,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06103864

Phase 3, Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for
Chronic Kidney Disease and Hypertension
Location: Cincinnati OH, Columbus OH, Indianapolis IN, Canton OH,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06742723

Phase 3, Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Cincinnati OH, Columbus OH, Ann Arbor MI, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase 3, Recruiting

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for
Atrial Fibrillation (AF), Persistant Atrial Fibrillation,
Location: Cincinnati OH, Columbus OH, Lexington KY, Ann Arbor MI,
Sponsor: Arga Medtech SA

Sex: All

Age: 18 - 70+

Code: NCT06784466

Recruiting

Neuroimaging Reveals Treatment-related Changes in DLD

for
Developmental Language Disorder
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 4 - 5

Code: NCT05268341

Recruiting

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for
Open tíbia Fracture
Location: Cincinnati OH, Indianapolis IN, London, Hamilton,
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT05615844

Phase 3, Recruiting

ELEVATE High-Risk PCI Pivotal Study

for
High-Risk Percutaneous Coronary Intervention (High-risk PCI)
Location: Cincinnati OH, Edgewood KY, Detroit MI, Chicago IL,
Sponsor: Magenta Medical Ltd.

Sex: All

Age: 18 - 70+

Code: NCT07001332

Recruiting

Aspiration Thrombectomy Using the Symphony or Prodigy System

for
Arterial Thromboembolism, Venous Thromboembolism,
Location: Cincinnati OH, Detroit MI, Munster IN, Naperville IL,
Sponsor: Imperative Care, Inc.

Sex: All

Age: 18+

Code: NCT07350499

Recruiting

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Cincinnati OH, Columbus OH, Detroit MI, Chicago IL,
Sponsor: Fate Therapeutics

Sex: All

Age: 18+

Code: NCT06241456

Phase 1, Recruiting

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Prostate Cancer
Location: Cincinnati OH, Indianapolis IN, Pittsburgh PA,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT04221542

Phase 1, Recruiting

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for
Breast Cancer
Location: Cincinnati OH, Chicago IL, Zion IL, St Louis MO,
Sponsor: Greenwich LifeSciences, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05232916

Phase 3, Recruiting

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for
Melanoma
Location: Cincinnati OH, Columbus OH, Fort Wayne IN, Lexington KY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06246916

Phase 3, Recruiting

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for
Metastatic Melanoma, Unresectable Melanoma, Melanoma
Location: Cincinnati OH, Columbus OH, Pittsburgh PA, Nashville TN,
Sponsor: Iovance Biotherapeutics, Inc.

Sex: All

Age: 18 - 70

Code: NCT05727904

Phase 3, Recruiting

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Cincinnati OH, Columbus OH, Louisville KY, Chicago IL,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06297226

Phase 2, Recruiting

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

for
Multiple Myeloma
Location: Cincinnati OH, Nashville TN, Roanoke VA, Fairfax VA,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT05972135

Phase 2, Recruiting

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

for
Metastatic HER2-positive Breast Cancer
Location: Cincinnati OH, Nashville TN, Roanoke VA, Milwaukee WI,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06435429

Phase 3, Recruiting

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors,
Location: Cincinnati OH, Nashville TN, Washington D.C. DC,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 1 - 70+

Code: NCT05868629

Recruiting