Discover hundreds of clinical trials in Ohio.
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With a robust healthcare network, renowned medical research centers, and innovative treatments, Ohio is a leading destination for a wide range of clinical trials. Institutions such as the Cleveland Clinic, Ohio State University Wexner Medical Center, University Hospitals Cleveland Medical Center, and Nationwide Children’s Hospital are at the forefront of these studies.
Ohio offers distinct advantages in the clinical research landscape. The state's diverse population provides a wide range of participants, enhancing the accuracy and relevance of research outcomes. Ohio is also recognized for its strong research environment, with a focus on medical innovation and pioneering studies in various fields.
By choosing to participate in a clinical trial in Ohio, participants contribute to vital medical research while benefiting from a well-established clinical trial infrastructure supported by top-tier healthcare institutions. This ensures they receive cutting-edge care and support throughout the process.
In Ohio, clinical trials cover a wide range of medical conditions and diseases, reflecting the state's diverse healthcare research landscape.
Ohio is home to leading cancer research centers like the Cleveland Clinic and Ohio State University Comprehensive Cancer Center, which conduct trials on various cancer types, including breast, lung, colorectal, and prostate cancers. These studies often focus on immunotherapies, targeted treatments, and novel drug combinations.
Oncology trials in Ohio are crucial due to the state’s significant cancer burden. Institutions like OSUCCC–James and the Cleveland Clinic are recognized for their commitment to groundbreaking research and patient care.
Institutions like the Cleveland Clinic and Ohio State University Wexner Medical Center are leaders in trials for neurological conditions, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), and stroke prevention. Research includes innovative therapies such as deep brain stimulation, new drug treatments, innovative diagnostics tools, and regenerative medicine.
Given the increasing prevalence of neurodegenerative diseases in Ohio’s aging population, these trials are vital for developing more effective treatments and improving the quality of life for patients.
Heart disease is a major focus in Ohio's clinical trials, with cardiovascular studies looking into advanced treatments for conditions like heart failure, coronary artery disease, congenital heart disorders, hypertension, and arrhythmias. These trials often explore the use of new medications, medical devices, and surgical interventions.
Research centers like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are conducting trials on innovative treatments such as gene therapies, advanced medical devices like pacemakers and stents, and novel drug therapies aimed at improving heart function and reducing mortality rates.
Conditions such as rheumatoid arthritis, lupus, inflammatory bowel disease, and Crohn's disease are commonly studied in Ohio. Leading institutions like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are conducting trials on novel biologics, immunosuppressive therapies, targeted therapies, and immunomodulatory drugs designed to better manage disease symptoms and halt progression.
Ohio conducts numerous clinical trials on diabetes, focusing on better glucose control, insulin delivery systems, and new medications aimed at managing both Type 1 and Type 2 diabetes, as well as related endocrine disorders. Major research institutions here also explore conditions like diabetic neuropathy, obesity, thyroid disorders, and metabolic syndrome.
With high rates of diabetes and obesity in the state, these trials are crucial for addressing public health concerns.
In Ohio, clinical trials for respiratory diseases focus on conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and cystic fibrosis as these are prevalent in the state.
Prominent institutions like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are leading trials on innovative treatments, including new inhalation therapies, biologics targeting specific inflammatory pathways, disease management strategies, and advanced drug delivery systems.
Clinical trials in Ohio are regulated through a combination of federal, state, and institutional guidelines to ensure participant safety and ethical conduct. Federal regulations from the FDA oversee the approval of new drugs and medical devices, while Institutional Review Boards (IRBs) review and approve trials to protect participants' rights, privacy, and welfare.
At the state level, the Ohio Department of Health enforces regulations that include strict informed consent requirements, ensuring participants are fully informed about the risks and benefits of a trial. Additionally, Ohio's leading medical institutions, such as the Cleveland Clinic and Ohio State University Wexner Medical Center, follow their own rigorous protocols for patient care and data management, while complying with HIPAA standards to protect patient privacy.
Joining a clinical trial provides early access to cutting-edge treatments and therapies before they become widely available, which is the primary benefit. The benefits for participants in clinical trials also include exceptional care by leading healthcare professionals, with comprehensive monitoring and specialized support throughout the study.
Moreover, participating in clinical trials is vital for advancing medical research, which can lead to transformative breakthroughs in treatments. By taking part, individuals gain access to pioneering medical solutions and play a key role in scientific progress, ultimately improving future healthcare outcomes for others.
Interested in participating in clinical trials but worried about how long they might take? Check out our comprehensive guide for all the information you need to make an informed decision.
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Sponsor:
Weill Medical College of Cornell University
Location:
Code:
NCT04124120
Conditions
Heart Diseases
Coronary Artery Disease
Coronary Artery Bypass Grafting
Eligibility Criteria
Sex: Female
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Single arterial graft
Multiple arterial grafting
Sponsor:
Checkpoint Surgical Inc.
Location:
Code:
NCT04662320
Conditions
Cubital Tunnel Syndrome
Nerve Compression
Nerve Injury
Ulnar Neuropathies
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Checkpoint BEST System
Sponsor:
Grifols Therapeutics LLC
Location:
Code:
NCT03702920
Conditions
Acute-On-Chronic Liver Failure
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
SMT + PE-A 5%
Standard Medical Treatment
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT03155620
Conditions
Advanced Malignant Solid Neoplasm
Ann Arbor Stage III Non-Hodgkin Lymphoma
Ann Arbor Stage IV Non-Hodgkin Lymphoma
Histiocytic Sarcoma
Juvenile Xanthogranuloma
Eligibility Criteria
Sex: All
Age: 12 - 21
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Bone Marrow Aspiration and Biopsy
Bone Scan
Computed Tomography
Sponsor:
medac GmbH
Location:
Code:
NCT05534620
Conditions
Acute Myeloid Leukaemia (AML)
Myelodysplastic Syndrome (MDS)
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Treosulfan
Fludarabine
Sponsor:
Biogen
Location:
Code:
NCT05798520
Conditions
Relapsing Forms of Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 55
Healthy Volunteers: Not accepted
Interventions
BIIB091
DRF
Placebo
Sponsor:
CinPhloro Pharma, LLC
Location:
Code:
NCT06153420
Conditions
Irritable Bowel Syndrome With Diarrhea
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
CIN-103
Placebo
Sponsor:
Takeda
Location:
Code:
NCT04779320
Conditions
Crohn's Disease (CD)
Eligibility Criteria
Sex: All
Age: 2 - 17
Healthy Volunteers: Not accepted
Interventions
Vedolizumab IV
Sponsor:
Jazz Pharmaceuticals
Location:
Code:
NCT05864846
Conditions
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Eligibility Criteria
Sex: All
Age: 1 - 65
Healthy Volunteers: Not accepted
Interventions
Cannabidiol Oral Solution [Epidiolex]