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Paid Clinical Trials Ontario

Discover 2,717 paid clinical trials in Ontario. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma,
Location: Toronto, Dallas TX, San Antonio TX
Sponsor: Auricula Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07148128

Phase1, Phase2, Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for
Aortic Stenosis
Location: Boston MA, New York NY, Albany NY, Summit NJ, Montreal,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 50 - 70+

Code: NCT05646381

Phase2, Recruiting

First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

for
Neoplasms
Location: Toronto, Montreal, Philadelphia PA, San Antonio TX
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07438782

Phase1, Recruiting

Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium

for
Postpartum Hemorrhage
Location: Toronto
Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Sex: Female

Age: 18 - 45

Code: NCT06285409

Recruiting

Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study

for
Postpartum Hemorrhage
Location: Toronto
Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Sex: Female

Age: 19 - 45

Code: NCT06285396

Recruiting

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AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02 (Nintedanib Solution) in IPF

for
Idiopathic Pulmonary Fibrosis (IPF)
Location: St. John's, Halifax, Trois-Rivieres, Montreal, Ajax,
Sponsor: Avalyn Pharma Inc.

Sex: All

Age: 40+

Code: NCT07194382

Phase2, Recruiting

Probiotic Research On Safety, Palatability, Efficacy and Receptivity

for
Probiotic Intervention
Location: Ottawa
Sponsor: Carleton University

Sex: Female

Age: 18 - 40

Code: NCT07512557

Recruiting

Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro Study

for
Hypotension
Location: Toronto
Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Sex: Female

Age: 19 - 40

Code: NCT04053478

Recruiting

Fampridine-SR and Optic Neuritis Recovery

for
Optic Neuritis
Location: London
Sponsor: Courtney Casserly

Sex: All

Age: 18 - 64

Code: NCT04148781

Early_phase1, Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Boston MA, Sherbrooke, Westbury NY, White Plains NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase2, Phase3, Recruiting

The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to Care

for
Syphilis
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 13 - 49

Code: NCT06829602

Recruiting

Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation Therapy

for
Prostate Cancer
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: Male

Age: 18+

Code: NCT06908694

Recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for
Invasive Mold Infections
Location: New York NY, Philadelphia PA, Baltimore MD, Ottawa,
Sponsor: Basilea Pharmaceutica

Sex: All

Age: 18+

Code: NCT06925321

Phase3, Recruiting

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

for
Early Alzheimer's Disease
Location: Newton MA, New Haven CT, Queens NY, Toms River NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 50 - 70+

Code: NCT07033494

Phase2, Recruiting

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

for
Psychosis Associated With Alzheimer's Disease
Location: Levis, West Long Branch NJ, Boca Raton FL,
Sponsor: MapLight Therapeutics

Sex: All

Age: 55 - 70+

Code: NCT06887192

Phase2, Recruiting

A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

for
Palmoplantar Pustulosis
Location: Fredericton, Elmhurst NY, Philadelphia PA, Hamilton,
Sponsor: LEO Pharma

Sex: All

Age: 18+

Code: NCT07013201

Phase2, Recruiting

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for
Follicular Lymphoma
Location: Towson MD, Fredericksburg VA, Roanoke VA, Toronto,
Sponsor: Celgene

Sex: All

Age: 18+

Code: NCT06911502

Phase3, Recruiting

Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure

for
Respiratory Insufficiency, Neuromuscular Blockade,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04524585

Recruiting

OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study

for
MDS, Myelodysplastic Syndromes,
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT06270771

Recruiting

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

for
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Location: Toronto, Edmonton, Calgary
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT06933173

Recruiting

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