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Paid Clinical Trials Toronto

Discover 2,121 paid clinical trials in Toronto, Ontario. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

for
Juvenile Psoriatic Arthritis
Location: Toronto, Cleveland OH, Valhalla NY, New York NY,
Sponsor: AbbVie

Sex: All

Age: 5 - 17

Code: NCT06100744

Phase 3, Recruiting
FeaturedActive & Responsive

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Toronto, Montreal, Grand Rapids MI, Philadelphia PA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT06619587

Phase 1, Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Vaughan, Rochester NY, Cleveland OH, Westlake OH,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase 3, Recruiting
Featured

A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

for
Moderately to Severely Active Ulcerative Colitis
Location: Toronto, Pittsburgh PA, New York NY, Lake Success NY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 2 - 17

Code: NCT07158242

Phase 3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

for
Von Willebrand Disease, Type 3
Location: Toronto, Montreal, Richmond VA, Lexington KY,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0+

Code: NCT06998524

Phase 3, Recruiting

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Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: Toronto, Amherst NY, Cleveland OH, Farmington Hills MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Toronto, Vaughan, London, Chesterfield MI, Westlake OH,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase 3, Recruiting
Featured

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for
Lymphoma
Location: Toronto, Rochester NY, London, East Syracuse NY, Ottawa,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06084936

Phase 3, Recruiting
Featured

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Toronto, London, Ann Arbor MI, Montreal, Fairfax VA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06820463

Phase 2, Recruiting
Featured

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for
Metastatic Castration-Resistant Prostate Cancer
Location: Toronto, Montreal, The Bronx NY, Providence RI,
Sponsor: Hoffmann-La Roche

Sex: Male

Age: 18+

Code: NCT07287150

Phase 2, Recruiting
Featured

A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for
Advanced Squamous Tumors
Location: Toronto, Grand Rapids MI, Montreal, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07241039

Phase 1, Recruiting
Featured

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

for
HER2-positive Breast Cancer
Location: Toronto, Ottawa, Albany NY, Montreal, Greenfield Park,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07413939

Phase 2, Phase 3, Recruiting
Featured

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

for
Cancer
Location: Toronto
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0+

Code: NCT05862285

Phase 3, Recruiting
Featured

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

for
Advanced Prostate Cancer, Metastatic Prostate Cancer
Location: Toronto, New Haven CT, Chicago IL, Nashville TX,
Sponsor: Genentech, Inc.

Sex: Male

Age: 18+

Code: NCT05800665

Phase 1, Recruiting
Featured

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

for
Neoplasms
Location: Toronto, New Haven CT, Sarasota FL, Houston TX,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06884618

Phase 1, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Toronto, Cleveland OH, Detroit ME, Canton OH,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase 1, Phase 2, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Toronto, Peterborough, Rochester NY, London, Ottawa,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase 3, Recruiting
Featured

Study of Glecaprevir/Pibrentasvir to Assess Safety Through Real-World Data

for
Hepatitis C Virus (HCV)
Location: Toronto, Vancouver
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07419347

Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Toronto, London, Cleveland OH, Clinton Township MI,
Sponsor: 89bio, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Toronto, Mayfield Heights OH, Cleveland OH, Detroit MI,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase 3, Recruiting