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Paid Clinical Trials Ontario

Discover 2,717 paid clinical trials in Ontario. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

The SWITCH (Substitution of High With Low Ultra-processed Soy Protein Foods In a Guideline-based Diet inTervention for Cardiometabolic Health) Trial

for
Hypertension in Type 2 Diabetes, Diabetes Mellitus Type 2,
Location: Toronto
Sponsor: University of Toronto

Sex: All

Age: 18+

Code: NCT06907862

Recruiting
Active & Responsive

SYNCED - SYNChronized Eating in Bipolar Depression Study

for
Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
Location: Ottawa
Sponsor: University of Ottawa

Sex: All

Age: 18 - 55

Code: NCT06560957

Recruiting
Active & Responsive

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for
Triple Negative Breast Neoplasms
Location: Quebec, Chicoutimi, Mineola NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06841354

Phase3, Recruiting
Active & Responsive

Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)

for
Treatment Resistant Depression
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 65

Code: NCT06512220

Phase2, Recruiting
Active & Responsive

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

for
Generalized Myasthenia Gravis
Location: Boston MA, Quebec, Washington D.C. DC, Ottawa,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06744920

Phase3, Recruiting

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Active & Responsive

MRI Guided Closed-loop TMS-EEG

for
Normal Physiology, Amnestic Mild Cognitive Impairment
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18 - 70+

Code: NCT06050603

Recruiting
Active & Responsive

Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression

for
Major Depressive Disorder (MDD),
Location: Ottawa
Sponsor: The Royal Ottawa Mental Health Centre

Sex: All

Age: 18 - 70+

Code: NCT06773949

Recruiting
Active & Responsive

Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

for
Pain, Sleep, Anxiety, Depression, Epilepsy
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 19+

Code: NCT04526093

Recruiting
Active & Responsive

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

for
Non-segmental Vitiligo
Location: The Bronx NY, Quebec, Norfolk VA, Hollywood FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07431177

Phase2, Recruiting
Active & Responsive

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for
Healthy
Location: Halifax, Boston MA, Quebec, East Setauket NY,
Sponsor: Pfizer

Sex: All

Age: 0 - 49

Code: NCT07160244

Phase3, Recruiting
Active & Responsive

Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery

for
Chronic Iron Deficiency Anaemia, Cardiac Surgery
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06287619

Phase2, Recruiting
Active & Responsive

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for
Primary Progressive Aphasia, Logopenic Progressive Aphasia,
Location: Philadelphia PA, Baltimore MD, Toronto
Sponsor: Johns Hopkins University

Sex: All

Age: 50 - 70+

Code: NCT05386394

Phase2, Recruiting
Active & Responsive

Sensory Motor Arousal Regulation Treatment (SMART) Study

for
PTSD, Post-traumatic Stress Disorder
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18 - 65

Code: NCT06035809

Recruiting
Active & Responsive

Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition

for
Long COVID, Post Acute Sequelae of COVID-19,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT06452095

Recruiting
Active & Responsive

Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression

for
Major Depressive Disorder (MDD)
Location: Toronto
Sponsor: Rotman Research Institute at Baycrest

Sex: All

Age: 60 - 70+

Code: NCT07212465

Recruiting
Active & Responsive

E-field Guided iTBS for Treatment Resistant Depression

for
Major Depressive Disorder
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 65

Code: NCT05583747

Recruiting
Active & Responsive

MDMA-Assisted CBCT for PTSD vs CBCT RCT

for
Post Traumatic Stress Disorder
Location: Toronto
Sponsor: Remedy

Sex: All

Age: 18 - 70+

Code: NCT06044675

Phase2, Recruiting
Active & Responsive

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

for
Diabetic Nephropathies, Kidney Failure, Chronic,
Location: Boston MA, The Bronx NY, Montreal, Syracuse NY, Toronto,
Sponsor: Alessandro Doria

Sex: All

Age: 18 - 70+

Code: NCT06217302

Phase3, Recruiting
Active & Responsive

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

for
Major Depressive Disorder
Location: Halifax, Ottawa, Kingston, Whitby, Toronto, Hamilton,
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18 - 65

Code: NCT05017311

Recruiting
Active & Responsive

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

for
Overweight, Obesity, Overweight and/or Obesity,
Location: Bridgewater, Chicoutimi, Hamilton NJ, Montreal, Mirabel,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07575932

Phase2, Recruiting

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