Paid Clinical Trials Columbia

Discover 214 paid clinical trials in Columbia, South Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 214

A Research Study to Advance the CF Therapeutics Pipeline for People Without ModulatorsA Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

Recruiting

Sponsor:

Nicole Hamblett

Location:

Columbia SC, Augusta GA, Charleston SC, Winston-Salem NCshow 58 more

Code:

NCT06504589

Conditions

Cystic Fibrosis

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Not accepted

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Recruiting

PHASE3

Sponsor:

NRG Oncology

Location:

Union SC, Rock Hill SC, Augusta GA, Monroe NCshow 706 more

Code:

NCT05879926

Conditions

Breast Cancer

Eligibility Criteria

Sex: Female

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Ovarian Function Suppression + Aromatase Inhibitor

Adjuvant Chemotherapy + Ovarian Function Suppression

Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)

Recruiting

Sponsor:

Vertex Pharmaceuticals Incorporated

Location:

Columbia SC, Durham NC, Richmond VA, Morgantown WVshow 22 more

Code:

NCT06506773

Conditions

Cystic Fibrosis

Eligibility Criteria

Sex: All

Age: 0 - 6

Healthy Volunteers: Not accepted

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Recruiting

PHASE3

Sponsor:

89bio, Inc.

Location:

Columbia SC, Charleston SC, Athens GA, Asheville NCshow 83 more

Code:

NCT06419374

Conditions

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Pegozafermin

Placebo

Reiterative Development and Evaluation Study of OSA Therapy SystemReiterative Development and Evaluation Study of OSA Therapy System

Recruiting

Sponsor:

ApniCure, Inc.

Location:

Columbia SC, Atlanta GA, Louisville KY, Chevy Chase MDshow 3 more

Code:

NCT01634074

Conditions

Obstructive Sleep Apnea

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Recruiting

PHASE3

Sponsor:

AstraZeneca

Location:

Columbia SC, Charleston SC, Statesville NC, Macon GAshow 125 more

Code:

NCT06268873

Conditions

Chronic Kidney Disease and Hypertension

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Baxdrostat/dapagliflozin

Dapagliflozin in combination with placebo

A Study to Evaluate Solrikitug in Participants With COPD (ZION)A Study to Evaluate Solrikitug in Participants With COPD (ZION)

Recruiting

PHASE2

Sponsor:

Uniquity One (UNI)

Location:

Columbia SC, Union SC, Rock Hill SC, Spartanburg SCshow 26 more

Code:

NCT06496620

Conditions

COPD

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Biological: Solrikitug low dose

Biological: Solrikitug high dose

Placebo

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder CancerTesting the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Union SC, Gaffney SC, Spartanburg SC, Greer SCshow 257 more

Code:

NCT04164082

Conditions

Bladder Flat Urothelial Carcinoma In Situ

Non-Muscle Invasive Bladder Urothelial Carcinoma

Stage 0a Bladder Cancer AJCC v8

Stage 0is Bladder Cancer AJCC v8

Stage I Bladder Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy

Biospecimen Collection

Computed Tomography

Cystoscopy

Gemcitabine Hydrochloride

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia ConditionsA Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

Recruiting

PHASE2

PHASE3

Sponsor:

Takeda

Location:

Columbia SC, Huntersville NC, Denver NC, Charleston SCshow 14 more

Code:

NCT05816382

Conditions

Narcolepsy Type 1

Eligibility Criteria

Sex: All

Age: 16 - 70

Healthy Volunteers: Not accepted

Interventions

TAK-861

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE TrialDeveloping an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

West Columbia SC, Union SC, Greenwood SC, Gaffney SCshow 198 more

Code:

NCT06216574

Conditions

Breast Cancer Female

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Internet-based Intervention