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Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

for
Leukemia, Myeloid, Chronic, Myeloid Leukemia,
Location: Baltimore MD, Toronto, Augusta GA, Cleveland OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT04260022

Phase1, Recruiting

Halt Aging in Survivors of Blood Cancers

for
Hematological Malignancy, Leukemia, Lymphoid Leukemia,
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 50+

Code: NCT07292272

Recruiting

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for
Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia,
Location: Philadelphia PA, Memphis TN, Duarte CA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 10 - 30

Code: NCT05194397

Phase2, Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for
B Acute Lymphoblastic Leukemia Associated With Down Syndrome,
Location: Providence RI, New Haven CT, The Bronx NY,
Sponsor: Children's Oncology Group

Sex: All

Age: 6 - 39

Code: NCT05702645

Recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

for
Acute Leukemia, Myelodysplastic Syndrome,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06265584

Phase2, Recruiting

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Umbilical Cord Blood Transplantation From Unrelated Donors

for
Acute Leukemia, Immune Deficiency Disorder,
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 0 - 70+

Code: NCT03016806

Recruiting

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for
Non-small Cell Lung Cancer,
Location: Boston MA, New York NY, New Brunswick NJ, Pittsburgh PA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT05877599

Phase1, Recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma,
Location: Charlotte NC, Memphis TN, Tulsa OK, San Diego CA
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06390319

Phase2, Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for
B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma,
Location: Valhalla NY, Chapel Hill NC, Jacksonville FL,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 13 - 70+

Code: NCT06533579

Phase1, Phase2, Recruiting

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

for
Blasts 10-19 Percent of Bone Marrow Nucleated Cells,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03896269

Phase1, Recruiting

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

for
Breast Cancer, Lung Cancer, Multiple Myeloma, Ovarian Cancer,
Location: Canton OH, Massillon OH, Cleveland OH, Evanston IL
Sponsor: Carevive Systems, Inc.

Sex: All

Age: 18+

Code: NCT05974150

Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for
Hematologic Malignancy, Leukemia, Lymphoma,
Location: Cincinnati OH, Milwaukee WI, Houston TX, Aurora CO
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 38

Code: NCT06131801

Recruiting

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

for
Fanconi Anemia, Severe Marrow Failure,
Location: Cincinnati OH, Seattle WA
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT02143830

Phase2, Recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma,
Location: Charlotte NC, Memphis TN, Baton Rouge LA, Tulsa OK,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 1 - 18

Code: NCT06289673

Recruiting

Subcutaneous Blinatumomab for Treatment of Adult Patients With CD19-Positive Mixed Phenotype Acute Leukemia (MPAL)

for
CD19 Positive, Mixed Phenotype Acute Leukemia (MPAL)
Location: Morgantown WV
Sponsor: West Virginia University

Sex: All

Age: 18+

Code: NCT07222579

Phase2, Recruiting

A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.

for
Acute Leukemia, High Risk, Myelodysplastic Syndromes, High Risk,
Location: Montreal
Sponsor: Ciusss de L'Est de l'Île de Montréal

Sex: All

Age: 18 - 67

Code: NCT07301866

Phase1, Phase2, Recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

for
GVHD,Acute, Acute Leukemia, Myelodysplastic Syndromes,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 60

Code: NCT06315309

Phase2, Recruiting

Q702 for the Treatment of Patients With Hematologic Malignancies

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06712810

Phase1, Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for
Hematologic Malignancies, Inherited Disorders of Metabolism,
Location: Boston MA, New Haven CT, Stony Brook NY, Lake Sucess NY,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 0+

Code: NCT01351545

Recruiting

BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)

for
Acute Leukemia, MDS
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 70+

Code: NCT04187105

Phase2, Recruiting