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Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

for
Acute Leukemia, Acute Lymphoblastic Leukemia,
Location: Pittsburgh PA, Tampa FL, Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 1 - 60

Code: NCT03970096

Phase2, Recruiting

Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Relapsed/Refractory Acute Myeloid Leukemia
Location: Newark DE, Canton OH, Atlanta GA, Houston TX, Aurora CO,
Sponsor: Nerviano Medical Sciences

Sex: All

Age: 18+

Code: NCT06549790

Phase1, Recruiting

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

for
Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06543381

Phase1, Recruiting

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

for
Acute Myeloid Leukemia
Location: Providence RI, Philadelphia PA, Chapel Hill NC,
Sponsor: Joshua Zeidner

Sex: All

Age: 18+

Code: NCT05442216

Phase2, Recruiting

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

for
Relapsed/Refractory Acute Myeloid Leukemia (AML),
Location: New York NY, Durham NC, Miami FL, Buffalo NY, Tampa FL,
Sponsor: Cullinan Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT05143996

Phase1, Recruiting

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Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT01311258

Recruiting

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

for
Relapsed Adult AML, Primary Refractory Acute Myeloid Leukemia,
Location: Boston MA, Philadelphia PA, Baltimore MD, Rochester NY,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT05237258

Recruiting

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

for
Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute,
Location: New York NY, Miami FL, Buffalo NY, Tampa FL,
Sponsor: BlossomHill Therapeutics

Sex: All

Age: 18+

Code: NCT06501196

Phase1, Recruiting

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

for
Refractory Acute Myeloid Leukemia,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 1+

Code: NCT06017258

Phase1, Recruiting

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

for
Acute Leukemia, Acute Myeloid Leukemia,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0 - 25

Code: NCT03810196

Recruiting

Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Location: Minneapolis MN
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 25

Code: NCT05014165

Recruiting

Phase I Study of HC-7366 for Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06285890

Phase1, Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for
Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma,
Location: Boston MA, Chapel Hill NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 13+

Code: NCT04771572

Phase1, Recruiting

Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission

for
Acute Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05010772

Phase1, Recruiting

Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy

for
Acute Myeloid Leukemia
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06279572

Recruiting

Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

for
Acute Myeloid Leukemia
Location: Miami FL, Indianapolis IN, Houston TX
Sponsor: Huda Salman

Sex: All

Age: 12+

Code: NCT06197672

Phase1, Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

for
Recurrent Childhood Acute Myeloid Leukemia,
Location: Miami FL
Sponsor: Florida International University

Sex: All

Age: 0 - 21

Code: NCT05857969

Phase1, Recruiting

Familial Investigations of Childhood Cancer Predisposition

for
Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0+

Code: NCT03050268

Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 39

Code: NCT05800210

Phase2, Recruiting

Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 2+

Code: NCT05580601

Phase1, Phase2, Recruiting