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A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Recurrent Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06763341

Phase1, Recruiting

Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

for
Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML),
Location: Pittsburgh PA
Sponsor: Sawa Ito, MD

Sex: All

Age: 18+

Code: NCT07565220

Phase1, Recruiting

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

for
Acute Myeloid Leukemias
Location: Montreal, Toronto, Shreveport LA, Goodyear AZ,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 12+

Code: NCT07211958

Phase3, Recruiting

8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05263284

Phase1, Recruiting

Caris Chromoseq Data Collection

for
Acute Myeloid Leukemia (AML),
Location: Phoenix AZ
Sponsor: Caris Science, Inc.

Sex: All

Age: 18+

Code: NCT07680868

Recruiting

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Individualized AML Treatment

for
Relapsed/Refractory Acute Myeloid Leukemia (AML)
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07613385

Recruiting

Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms

for
Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07094750

Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for
Acute Myeloid Leukemia Post Cytotoxic Therapy,
Location: New York NY, Philadelphia PA, Pittsburgh PA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 21

Code: NCT07012044

Phase1, Recruiting

Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse
Location: Boston MA
Sponsor: David Avigan

Sex: All

Age: 0+

Code: NCT07374029

Phase1, Recruiting

PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia

for
Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02390635

Phase1, Recruiting

High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Iowa City IA
Sponsor: Kittika Poonsombudlert

Sex: All

Age: 18 - 70+

Code: NCT07177079

Phase1, Recruiting

Venetoclax Basket Trial for High Risk Hematologic Malignancies

for
Myelodysplastic Syndromes, de Novo,
Location: Boston MA, Atlanta GA, Chicago IL, Aurora CO,
Sponsor: Andrew E. Place, MD

Sex: All

Age: 1 - 40

Code: NCT05292664

Phase1, Recruiting

Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies

for
Myeloid Malignancy, Hematologic Malignancy,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT07044544

Phase1, Recruiting

FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: The Bronx NY
Sponsor: Montefiore Medical Center

Sex: All

Age: 18+

Code: NCT07283094

Phase1, Recruiting

Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: New York NY, Houston TX
Sponsor: Remedy Plan, Inc.

Sex: All

Age: 18+

Code: NCT07107126

Phase1, Recruiting

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06672146

Phase2, Recruiting

Olutasidenib Single Plus Combo Therapy in IDH1mut AML After Induction and Consolidation

for
Acute Myeloid Leukemia
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT07130695

Phase1, Recruiting

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

for
Leukemia, Acute Myeloid Leukemia,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 25

Code: NCT06810583

Phase1, Recruiting

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, in Relapse,
Location: Charlottesville VA
Sponsor: Keystone Nano, Inc

Sex: All

Age: 18+

Code: NCT04716452

Phase1, Recruiting

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for
Acute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)
Location: York PA, Bethesda MD, Charlotte NC, Columbus OH,
Sponsor: Tempus AI

Sex: All

Age: 0+

Code: NCT07154823

Recruiting