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A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
Location: Philadelphia PA, Fairfax VA, Cleveland OH,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07490301

Phase2, Phase3, Recruiting
Featured

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

for
Hepatocellular Carcinoma, Pancreatic Ductal Adenocarcinoma,
Location: San Antonio TX
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06084481

Phase1, Recruiting
Active & Responsive

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: New York NY, Belleville NJ, Philadelphia PA, Newark DE,
Sponsor: Immuneering Corporation

Sex: All

Age: 18+

Code: NCT07562152

Phase3, Recruiting
Active & Responsive

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

for
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Alterome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06835569

Phase1, Recruiting
Active & ResponsiveNew

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Tampa FL
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07805954

Phase3, Recruiting

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Active & Responsive

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

for
Non Small Cell Lung Cancer, Pancreatic Ductal Adenocarcinoma
Location: Fairfax VA, Huntersville NC, Nashville TN,
Sponsor: Phanes Therapeutics

Sex: All

Age: 18+

Code: NCT05431270

Phase1, Phase2, Recruiting
Active & Responsive

Pancreatic Cancer Detection Consortium

for
Pancreatic Cancer, Pancreatic Carcinoma,
Location: Morristown NJ, Rock Hill SC, Milwaukee WI, Peoria IL,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06388967

Recruiting
Active & Responsive

The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer

for
Pancreatic Cancer Stage III, Pancreatic Cancer Stage IV,
Location: Norwalk CT
Sponsor: Nuvance Health

Sex: All

Age: 18+

Code: NCT04406831

Recruiting
Active & Responsive

Samuraciclib for the Treatment of Patients With Resectable, Borderline Resectable, or Locally Advanced Basal Pancreatic Cancer

for
Resectable Pancreatic Ductal Adenocarcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT07645651

Phase1, Recruiting
Active & Responsive

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

for
Glioblastoma Multiforme (GBM),
Location: Houston TX
Sponsor: Radiomedix, Inc.

Sex: All

Age: 18+

Code: NCT07733674

Phase1, Recruiting
Active & Responsive

A Screening Program to Improve the Early Detection of Sporadic Pancreatic Cancer in Individuals With a High-Risk of Developing Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 50 - 70+

Code: NCT07324096

Recruiting
Active & Responsive

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

for
Locally Advanced Pancreatic Adenocarcinoma,
Location: Detroit MI, Houston TX, Santa Fe NM, Irvine CA,
Sponsor: Xerient Pharma

Sex: All

Age: 18+

Code: NCT07157033

Phase1, Phase2, Recruiting
Active & Responsive

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

for
Solid Tumor, Non-Small-Cell Lung Cancer,
Location: New York NY, Hackensack NJ, Fairfax VA, Buffalo NY,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT07094204

Phase1, Recruiting
Active & Responsive

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

for
Triple Negative Breast Cancer, HER2-negative Breast Cancer,
Location: Fairfax VA, Orlando FL, Huntersville NC, Sarasota FL,
Sponsor: Dren Bio

Sex: All

Age: 18+

Code: NCT06999187

Phase1, Recruiting
Active & Responsive

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Boston MA, New York NY, Durham NC
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07024615

Phase1, Recruiting
Active & Responsive

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

for
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma,
Location: Mineola NY, New York NY, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06428409

Phase1, Phase2, Recruiting
Active & Responsive

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06648434

Phase1, Recruiting
Active & Responsive

EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT05723107

Phase1, Recruiting
Active & Responsive

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

for
Prostate Cancer Castration-resistant Prostate Cancer,
Location: East Brunswick NJ, Fairfax VA, Grand Rapids MI,
Sponsor: MBrace Therapeutics

Sex: All

Age: 18+

Code: NCT07145255

Phase1, Phase2, Recruiting
New

Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life

for
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Location: Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT07255001

Recruiting