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A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

for
Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, PDAC,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06151223

Recruiting

AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma

for
Pancreatic Ductal Adenocarcinoma
Location: West Islip NY, Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06320717

Recruiting

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for
Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC),
Location: Boston MA, New Haven CT, New York NY, Baltimore MD,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06040541

Phase1, Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

for
Gastric Cancer, Gastroesophageal Junction Cancer,
Location: Providence RI, Sherbrooke, Commack NY, Montreal,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06219941

Phase2, Recruiting

ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)

for
Pancreatic Ductal Adenocarcinoma (PDAC)
Location: Birmingham AL
Sponsor: ProDa BioTech, LLC

Sex: All

Age: 18+

Code: NCT06182072

Phase1, Recruiting

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18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

for
Sarcoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06503146

Phase2, Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for
Advanced Cancer, Metastatic Cancer, Ovarian Cancer,
Location: Lake Success NY, Philadelphia PA, East Syracuse NY,
Sponsor: Artios Pharma Ltd

Sex: All

Age: 18+

Code: NCT04657068

Phase1, Phase2, Recruiting

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 18+

Code: NCT05132504

Phase2, Recruiting

A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Detroit MI, Houston TX
Sponsor: Oncotelic Inc.

Sex: All

Age: 18+

Code: NCT06079346

Phase2, Phase3, Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for
Solid Tumors With HRAS Alterations,
Location: Boston MA, New Brunswick NJ, Pittsburgh PA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06026410

Phase1, Recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

for
Borderline Resectable Pancreatic Ductal Adenocarcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06423326

Phase2, Recruiting

A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy

for
Pancreatic Ductal Adenocarcinoma
Location: Milwaukee WI
Sponsor: Mandana Kamgar, MD

Sex: All

Age: 18+

Code: NCT05630989

Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for
Colorectal Cancer, CRC, Pancreatic Ductal Adenocarcinoma, PDAC,
Location: Boston MA, New Haven CT, Lake Success NY, New York NY,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06445062

Phase1, Phase2, Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

for
Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer,
Location: Boston MA, Montreal, Toronto, Jacksonville FL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06562192

Phase1, Recruiting

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung,
Location: Boston MA, Montreal, Baltimore MD, Ottawa, Toronto,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT06131840

Phase1, Recruiting

Monitoring and Managing Glucose Levels in People With Pancreatic Cancer

for
Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Toronto, Vancouver
Sponsor: British Columbia Cancer Agency

Sex: All

Age: 18+

Code: NCT05132244

Recruiting

Determining the Link Between Dietary Patterns, Fecal Microbiome and Response to Neoadjuvant Chemotherapy

for
Borderline Resectable Pancreatic Ductal Adenocarcinoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06595160

Recruiting

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07199764

Phase2, Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

for
Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS
Location: Boston MA, New York NY, East Brunswick NJ, Baltimore MD,
Sponsor: Verastem, Inc.

Sex: All

Age: 18+

Code: NCT07644559

Phase2, Recruiting

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

for
Advanced Solid Tumor, Non-Small Cell Lung Cancer,
Location: Fairfax VA, Tampa FL, Sarasota FL
Sponsor: Blueprint Medicines Corporation

Sex: All

Age: 18+

Code: NCT07629960

Phase1, Phase2, Recruiting