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A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

for
Neoplasms
Location: Lake Success NY
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07277270

Phase1, Recruiting

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

for
Neoplasm Malignant
Location: New Brunswick NJ, Montreal, Baltimore MD, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07209111

Phase2, Recruiting

A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors

for
Solid Tumours
Location: Pittsburgh PA, Sioux Falls SD, Fort Worth TX,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07160725

Phase1, Phase2, Recruiting

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

for
Advanced-stage Solid Tumors
Location: Orlando FL, Irving TX
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07223125

Phase1, Recruiting

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

for
Non-Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer,
Location: Philadelphia PA, Minneapolis MN, Houston TX,
Sponsor: Fate Therapeutics

Sex: All

Age: 18+

Code: NCT07216105

Phase1, Recruiting

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A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

for
Advanced/Metastatic Solid Tumors, Bladder Cancer,
Location: Boston MA, Newton MA, New Haven CT, Trumbull CT,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07090499

Phase1, Recruiting

Intratumoral N17350 in Advanced Solid Tumors

for
Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative,
Location: Buffalo NY
Sponsor: Onchilles Pharma Inc

Sex: All

Age: 18+

Code: NCT07339176

Phase1, Phase2, Recruiting

A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)

for
Tumours, Gynecological
Location: Toronto, Montreal, Rochester NY, Durham NC, Columbus OH,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06796907

Phase1, Phase2, Recruiting

A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)

for
Metastatic Neoplasm
Location: Hackensack NJ, Chicago IL, Houston TX
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT07030712

Phase1, Recruiting

A Study of ZW251 in Participants With Advanced Solid Tumors

for
Hepatocellular Carcinoma,
Location: New York NY, Hackensack NJ, Louisville KY,
Sponsor: Zymeworks BC Inc.

Sex: All

Age: 18+

Code: NCT07164313

Phase1, Recruiting

ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors

for
HR+/HER2- Breast Cancer, HR+, HER2-, Advanced Breast Cancer
Location: New York NY, Sarasota FL, Houston TX, New Haven CT,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06998407

Phase1, Phase2, Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor

for
Advanced Liver Cancer
Location: New York NY, Jacksonville FL, Tampa FL, Rochester MN,
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18 - 70+

Code: NCT04906434

Phase1, Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

for
Breast Cancer, Ovarian Cancer, Endometrial Cancer,
Location: Fairfax VA, Houston TX, San Antonio TX, Los Angeles CA
Sponsor: Regor Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT07524322

Phase1, Recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

for
ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC),
Location: Lake Success NY, East Brunswick NJ, Fairfax VA,
Sponsor: IDEAYA Biosciences

Sex: All

Age: 18 - 70+

Code: NCT07540572

Phase1, Recruiting

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT05985655

Phase1, Phase2, Recruiting

First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors

for
Solid Tumors (Phase 1)
Location: New Haven CT, Springdale AR, Houston TX
Sponsor: Adcendo ApS

Sex: All

Age: 18+

Code: NCT07362888

Phase1, Recruiting

First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

for
Neoplasms
Location: Toronto, Montreal, Philadelphia PA, San Antonio TX
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07438782

Phase1, Recruiting

A Study of HS-20110 in Participants With Advanced Solid Tumors

for
Solid Tumors
Location: Fairfax VA, Tamarac FL, Huntersville NC, Fort Wayne IN,
Sponsor: Hansoh BioMedical R&D Company

Sex: All

Age: 18+

Code: NCT06892379

Phase1, Recruiting

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

for
Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma,
Location: San Antonio TX
Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: All

Age: 18+

Code: NCT04443088

Phase1, Recruiting

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for
PROC, Platinum Resistant Ovarian Cancer, Endometrial Cancer
Location: Long Island City NY, Philadelphia PA, Sarasota FL,
Sponsor: Whitehawk Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07470853

Phase1, Recruiting