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IDOV-Immune for Advanced Solid Tumors

for
Colorectal Cancer, Pancreatic Cancer, Melanoma, Ovarian Cancer,
Location: St Louis MO, Houston TX, San Antonio TX
Sponsor: ViroMissile, Inc.

Sex: All

Age: 18+

Code: NCT06910657

Phase1, Recruiting

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

for
Nasopharyngeal Carcinoma, Castrate Resistant Prostate Cancer,
Location: Springdale AR
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT05415098

Phase1, Recruiting

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

for
Ovarian Cancer, Melanoma, Triple Negative Breast Cancer,
Location: Fairfax VA, Dallas TX
Sponsor: Hefei TG ImmunoPharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT05746897

Phase1, Recruiting

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

for
Non Small Cell Lung Cancer,
Location: Boston MA, Austin, TX 78758 TX, San Antonio TX
Sponsor: Zumutor Biologics Inc.

Sex: All

Age: 18+

Code: NCT06451497

Phase1, Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for
Cancer, Advanced Cancer, Locally Advanced Carcinoma,
Location: Fairfax VA, Sarasota FL, Nashville TN, St Louis MO,
Sponsor: Angiex, Inc.

Sex: All

Age: 18+

Code: NCT06440005

Phase1, Recruiting

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Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma

for
Solid Tumor, Soft Tissue Sarcoma, Metastatic Sarcoma, Sarcoma
Location: Durham NC, Chapel Hill NC, Santa Monica CA
Sponsor: NanoCarrier Co., Ltd.

Sex: All

Age: 18 - 70+

Code: NCT03168061

Phase1, Phase2, Recruiting

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Los Angeles CA
Sponsor: BioInvent International AB

Sex: All

Age: 18+

Code: NCT04219254

Phase1, Phase2, Recruiting

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors

for
Solid Tumor
Location: Dallas TX
Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All

Age: 18+

Code: NCT05244551

Phase1, Recruiting

Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors

for
Advanced Refractory Solid Tumors,
Location: New Haven CT, Ohio City OH, Michigan Center MI,
Sponsor: Cosmo Technologies Ltd

Sex: All

Age: 18+

Code: NCT03863145

Early_phase1, Recruiting

A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation

for
KRAS P.G12C
Location: Sarasota FL, Detroit MI, Nashville TN, Houston TX,
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT05410145

Phase1, Phase2, Recruiting

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

for
Solid Tumor, Adult, Colorectal Cancer,
Location: Houston TX
Sponsor: Crossignal Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06598007

Phase1, Phase2, Recruiting

First In Human Study of CX-2051 in Advanced Solid Tumors

for
Solid Tumor, Adult
Location: Boston MA, The Bronx NY, Fairfax VA, Huntersville NC,
Sponsor: CytomX Therapeutics

Sex: All

Age: 18+

Code: NCT06265688

Phase1, Recruiting

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

for
Neoplasms
Location: New York NY, Montreal, Toronto, Pittsburgh PA,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18+

Code: NCT06311578

Phase1, Recruiting

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for
Solid Tumors
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: ORIC Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05315700

Phase1, Phase2, Recruiting

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for
Carcinoma, Non-Small Cell Lung,
Location: Boston MA, Newton MA, Shirley NY, Riverhead NY,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT04389632

Phase1, Recruiting

A Study of ASP3082 in Adults With Advanced Solid Tumors

for
Solid Tumor
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Astellas Pharma Inc

Sex: All

Age: 18+

Code: NCT05382559

Phase1, Recruiting

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Columbus OH, Grand Rapids MI, Houston TX,
Sponsor: Tanabe Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT06943521

Phase1, Phase2, Recruiting

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

for
Advanced HR+/HER2- Breast Cancer,
Location: Boston MA, New York NY, Montreal, Toronto,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT06726148

Phase1, Phase2, Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for
Solid Tumors, Advanced Cancer, Renal Cancer, Gastric Cancer,
Location: Montreal, Hershey PA, Chapel Hill NC, Toronto,
Sponsor: Apollomics Inc.

Sex: All

Age: 18+

Code: NCT03175224

Phase2, Recruiting

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies

for
Solid Tumor, Adult
Location: Commack NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Effector Therapeutics

Sex: All

Age: 18+

Code: NCT04092673

Phase1, Phase2, Recruiting