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A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

for
Advanced Solid Tumors
Location: New York NY, Fairfax VA, Margate FL, Plantation FL,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT05914116

Phase1, Phase2, Recruiting

Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: Pyxis Oncology, Inc

Sex: All

Age: 18+

Code: NCT06795412

Phase1, Phase2, Recruiting

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

for
Advanced Solid Tumor, Refractory Hodgkin Lymphoma
Location: Greenville SC
Sponsor: FBD Biologics Limited

Sex: All

Age: 18+

Code: NCT06487624

Phase1, Recruiting

A Study of ASP1002 in Adults for Treatment of Solid Tumors

for
Advanced Solid Tumors
Location: Plainville CT, New Haven CT, New York NY, Fairfax VA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT05719558

Phase1, Recruiting

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA, Fairfax VA,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06589596

Phase1, Recruiting

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Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

for
Locally Advanced Solid Tumor
Location: Boston MA, New York NY, Fairfax VA, Miami FL,
Sponsor: Tango Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05732831

Phase1, Phase2, Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase1, Phase2, Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for
Solid Tumor, Advanced Solid Tumor, Solid Tumor, Adult,
Location: Boston MA, Hackensack NJ, Philadelphia PA, Fairfax VA,
Sponsor: NiKang Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06586957

Phase1, Recruiting

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for
Advanced Solid Tumor, NSCLC (Non-small Cell Lung Cancer),
Location: New York NY, Fairfax VA, Jacksonville FL, Cleveland OH,
Sponsor: Nuvectis Pharma, Inc.

Sex: All

Age: 18+

Code: NCT05873686

Phase1, Recruiting

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: New York NY, Hackensack NJ, Philadelphia PA,
Sponsor: Clasp Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06778863

Phase1, Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06302621

Phase1, Recruiting

A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor, Solid Tumor
Location: New Haven CT, New York NY, Hackensack NJ, Miami FL,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT05981703

Phase1, Recruiting

A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Providence RI, Fairfax VA, Salt Lake City UT,
Sponsor: Peel Therapeutics Inc

Sex: All

Age: 18+

Code: NCT05329103

Phase1, Recruiting

The Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Atlanta GA, Louisville KY, Fairway KS, Dallas TX,
Sponsor: Impact Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04768868

Phase1, Recruiting

First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor
Location: Providence RI, Sarasota FL, Milwaukee WI, Westwood KS,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT05875168

Phase1, Phase2, Recruiting

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

for
Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer,
Location: Austin TX, San Antonio TX, Scottsdale AZ
Sponsor: OncoResponse, Inc.

Sex: All

Age: 18+

Code: NCT05094804

Phase1, Phase2, Recruiting

SNV4818 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Philadelphia PA, Ottawa, Toronto,
Sponsor: Pikavation Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06736704

Phase1, Phase2, Recruiting

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Jacksonville FL, Tampa FL, Sarasota FL,
Sponsor: Vividion Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05954312

Phase1, Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

for
Advanced Cancer, Advanced Solid Tumor, Melanoma, Metastasis,
Location: Providence RI, Lebanon NH, Houston TX, Aurora CO
Sponsor: 7 Hills Pharma, LLC

Sex: All

Age: 18+

Code: NCT06362369

Phase1, Phase2, Recruiting

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

for
Advanced Solid Tumor Cancer
Location: Washington D.C. DC, Durham NC, Charlotte NC,
Sponsor: Immunolight, LLC

Sex: All

Age: 18+

Code: NCT04389281

Phase1, Recruiting