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Study of SGR-3515 In Participants With Advanced Solid Tumors.

for
Advanced Solid Tumor
Location: New Haven CT, New York NY, Fairfax VA, Toronto,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT06463340

Phase1, Recruiting

A Beta-only IL-2 ImmunoTherapY Study

for
Advanced Solid Tumor, Unresectable Solid Tumor,
Location: Boca Raton FL, Toronto, Detroit MI, Atlanta GA,
Sponsor: Medicenna Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05086692

Phase1, Phase2, Recruiting

A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer

for
Advanced Solid Tumor, Hepatocellular Carcinoma
Location: Montreal, Lexington VA, Orlando FL, Toronto,
Sponsor: TORL Biotherapeutics, LLC

Sex: All

Age: 18+

Code: NCT06005740

Phase1, Recruiting

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for
Metastatic Solid Tumor, Advanced Solid Tumor
Location: Lake Success NY, New York NY, Fairfax VA, Pittsburgh PA,
Sponsor: Coherus Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06657144

Phase1, Recruiting

Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors

for
Advanced Solid Tumor
Location: San Francisco CA
Sponsor: Robert Bok, MD, PhD

Sex: All

Age: 18+

Code: NCT05599048

Phase1, Phase2, Recruiting

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A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Providence RI, New Haven CT, Miami FL, Charleston SC,
Sponsor: Eikon Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT06253130

Phase1, Phase2, Recruiting

ORB-021 In Patients With Advanced Solid Tumors

for
Advanced Solid Tumors Cancer
Location: Houston TX, Scottsdale AZ
Sponsor: Orionis Biosciences Inc

Sex: All

Age: 18+

Code: NCT06607939

Phase1, Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

for
NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor,
Location: Pittsburgh PA, Irvine CA
Sponsor: CJ Bioscience, Inc.

Sex: All

Age: 18+

Code: NCT05877430

Phase1, Phase2, Recruiting

Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

for
Advanced Solid Tumors
Location: Cincinnati OH, Houston TX, Salt Lake City UT
Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All

Age: 18+

Code: NCT06096974

Phase1, Recruiting

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

for
Cancer, Advanced Cancer, Advanced Solid Tumor,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05166694

Recruiting

A Study of BG-C477 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: New Haven CT, Hackensack NJ, Peoria IL, Westwood KS,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06596473

Phase1, Recruiting

Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Boston MA, Toronto, Nashville TN, Madison WI,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT05007782

Phase1, Recruiting

A Study of ASKG915 in Patients With Selected Advanced Solid Tumors.

for
Advanced Solid Tumors
Location: New York NY, Pittsburgh PA
Sponsor: AskGene Pharma, Inc.

Sex: All

Age: 18+

Code: NCT05867420

Phase1, Phase2, Recruiting

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

for
Solid Tumors, Advanced Solid Tumor
Location: Fairfax VA, Houston TX, San Antonio TX
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07181681

Phase1, Recruiting

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

for
Advanced Solid Tumors
Location: Grand Rapids MI, San Antonio TX, West Valley City UT
Sponsor: ModernaTX, Inc.

Sex: All

Age: 18+

Code: NCT06880549

Phase1, Recruiting

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

for
Advanced Solid Tumor, Metastatic Solid Tumor,
Location: Lake Success NY, Buffalo NY, Sarasota FL,
Sponsor: InduPro, Inc.

Sex: All

Age: 18+

Code: NCT07602842

Phase1, Phase2, Recruiting

A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Lake Success NY
Sponsor: LigaChem Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07460375

Phase1, Phase2, Recruiting

Study of GS-2426 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: New York NY, East Brunswick NJ, Grand Rapids MI,
Sponsor: Gilead Sciences

Sex: All

Age: 18+

Code: NCT07601243

Phase1, Recruiting

A Study of Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation

for
Advanced Solid Tumors
Location: San Antonio TX
Sponsor: Nutshell Therapeutics (Shanghai) Co., LTD.

Sex: All

Age: 18+

Code: NCT07060989

Phase1, Phase2, Recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for
Gastric Cancer, Gastric Adenocarcinoma,
Location: Fairfax VA
Sponsor: BigHat Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07529808

Phase1, Phase2, Recruiting