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Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl

for
Alzheimer Disease
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06439992

Recruiting

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

for
Diabetes, Alzheimer's Disease (Incl Subtypes), Dementia,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 65+

Code: NCT05643144

Recruiting

UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy

for
Alzheimer Disease
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 50+

Code: NCT03809351

Phase1, Recruiting

Daridorexant for Alzheimer Disease Prevention

for
Alzheimer Disease (AD)
Location: Montreal
Sponsor: Douglas Mental Health University Institute

Sex: All

Age: 50 - 70+

Code: NCT07213349

Phase2, Recruiting

Sleep Trial to Prevent Alzheimer's Disease

for
Sleep, Alzheimer Disease
Location: St Louis MO
Sponsor: University of Minnesota

Sex: All

Age: 65+

Code: NCT04629547

Phase2, Recruiting

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A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

for
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Location: Maitland FL, Naples FL
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 40 - 55

Code: NCT07636811

Phase2, Recruiting

Alzheimer's Tau Platform: Master Protocol

for
Preclinical Alzheimer's Disease, Alzheimer Disease,
Location: Providence RI, Nashville TN, San Francisco CA
Sponsor: Paul S. Aisen

Sex: All

Age: 50 - 70+

Code: NCT06957418

Phase2, Recruiting

NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE

for
Alzheimer s Disease,
Location: Houston TX
Sponsor: Chi-Ying (Roy) Lin

Sex: All

Age: 55 - 70+

Code: NCT07667478

Recruiting

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

for
Down Syndrome, Down Syndrome, Partial Trisomy 21,
Location: Nashville TN
Sponsor: Vanderbilt University Medical Center

Sex: All

Age: 18 - 55

Code: NCT05231798

Phase2, Recruiting

Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease

for
Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease,
Location: New York NY
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 50+

Code: NCT07553338

Phase2, Recruiting

Late Onset Alzheimer's Disease

for
Alzheimer Disease
Location: New York NY, Raleigh NC, Miami FL, Pittsburgh PA,
Sponsor: Columbia University

Sex: All

Age: 55+

Code: NCT05010603

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

for
Psychosis Associated With Alzheimer's Disease
Location: Stuart FL, Viera FL, Cypress TX
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06126224

Phase3, Recruiting

Biomarker-based Trial of NPC-1 for Alzheimer's Pathology

for
Alzheimer Disease, Mild Cognitive Impairment (MCI),
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 55+

Code: NCT07236190

Phase2, Recruiting

Tele-Savvy for Latino Caregivers

for
Alzheimer Disease, Dementia, Caregiver Stress
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT07290387

Recruiting

Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease

for
Alzheimer Disease, Lymphatic Obstruction
Location: Buffalo NY, Jacksonville FL, Palo Alto CA
Sponsor: MMI (Medical Microinstruments, Inc.)

Sex: All

Age: 50+

Code: NCT07178210

Recruiting

Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

for
Agitation Associated With Alzheimer's Disease Dementia
Location: Bennington VT, Brooklyn NY, New York NY, Peterborough,
Sponsor: Exciva GmbH

Sex: All

Age: 55 - 70+

Code: NCT07284472

Phase2, Phase3, Recruiting

Levetiracetam for Persons at Risk for Alzheimer's Disease

for
Hippocampal Hyperactivation, Prodromal Alzheimer Disease
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 55 - 70+

Code: NCT07477431

Phase2, Recruiting

Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

for
Dementia, Alzheimers Disease,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 60 - 70+

Code: NCT06489548

Phase2, Recruiting

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

for
Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier,
Location: New Brunswick NJ
Sponsor: Michal Schnaider Beeri, Ph.D.

Sex: All

Age: 60+

Code: NCT07392723

Phase2, Recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

for
Alzheimer Disease,
Location: St Louis MO
Sponsor: University College, London

Sex: All

Age: 21 - 70+

Code: NCT06372821

Phase1, Recruiting