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A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for
Alzheimers Disease
Location: Halifax, Boston MA, Watertown MA, New Haven CT,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07170150

Phase3, Recruiting
Featured

A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

for
Alzheimer's Disease
Location: Watertown MA, Wellington FL, Stuart FL, Winter Park FL,
Sponsor: AbbVie

Sex: All

Age: 50 - 70+

Code: NCT07599670

Phase1, Phase2, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: Halifax, Boston MA, Watertown MA, Newton MA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase3, Recruiting
Featured

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for
Alzheimers Disease
Location: Boston MA, Newton MA, Providence RI, Quebec,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07169578

Phase3, Recruiting
Active & Responsive

Genetic Studies of Early-onset Dementia

for
Dementia, Early Onset, Alzheimer Dementia (AD),
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 35+

Code: NCT04906863

Recruiting

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Active & Responsive

Predicting Pre-dementia

for
Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD),
Location: San Diego CA
Sponsor: Prevention Research Consortium Corp.

Sex: All

Age: 55+

Code: NCT07516119

Recruiting
Active & Responsive

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

for
Mild Cognitive Impairment, Alzheimer Dementia (AD)
Location: Austin TX
Sponsor: University of Texas at Austin

Sex: All

Age: 18 - 70+

Code: NCT05907343

Recruiting
Active & Responsive

Low-Dose Radiotherapy for Alzheimer's Disease

for
Alzheimer Dementia, Dementia, Alzheimer Dementia (AD),
Location: Winter Park FL
Sponsor: Evan Thomas

Sex: All

Age: 50+

Code: NCT07693140

Phase1, Phase2, Recruiting
Active & Responsive

ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

for
Alzheimer Disease
Location: Fort Lauderdale FL, Delray Beach FL, Miami FL,
Sponsor: InSightec

Sex: All

Age: 50 - 70+

Code: NCT03671889

Recruiting
Active & Responsive

Repurposing Siponimod for Alzheimer's Disease

for
Alzheimer Disease, Mild Alzheimer Disease,
Location: Phoenix AZ
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 50 - 70+

Code: NCT06639282

Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for
Alzheimer's Disease
Location: Halifax, East Providence RI, Newton MA, Quebec,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 60 - 70+

Code: NCT06976216

Phase3, Recruiting
Active & Responsive

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Location: Providence RI, New Haven CT, Quebec, New York NY,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06647498

Phase2, Phase3, Recruiting
Active & Responsive

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Location: Providence RI, New Haven CT, Quebec, New York NY,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05552157

Phase2, Phase3, Recruiting
Active & Responsive

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for
Alzheimer Disease
Location: North Dartmouth MA, Boston MA, Belmont MA,
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All

Age: 55 - 70+

Code: NCT06585787

Phase3, Recruiting
Active & Responsive

Study to Understand Novel Biomarkers in Researching Dementia

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 60+

Code: NCT06547099

Recruiting
Active & Responsive

Retinal Imaging in Neurodegenerative Disease

for
Alzheimer's Disease, Mild Cognitive Impairment,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT03233646

Recruiting
Active & Responsive

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

for
Alzheimer Disease
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: Female

Age: 60+

Code: NCT03821857

Recruiting
Active & Responsive

ADRC Clinical Cohort (Alzheimer's Disease)

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 25 - 70+

Code: NCT06703541

Recruiting
Active & Responsive

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

for
Depressive Symptoms, Depression, Alzheimer Disease,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18 - 70+

Code: NCT04123314

Early_phase1, Recruiting
Active & Responsive

Alzheimer's Disease Genetics Study

for
Alzheimer Disease, Late Onset Alzheimer Disease, Dementia
Location: Nationwide IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT00064870

Recruiting