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A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

for
Alzheimer Disease, Dementia, Plaque, Amyloid
Location: Newton MA, Springfield NJ, Aventura FL, Miami FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 55+

Code: NCT07602582

Phase3, Recruiting

Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease

for
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Location: Boston MA
Sponsor: Boston University Charles River Campus

Sex: All

Age: 50 - 70+

Code: NCT07659964

Recruiting

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

for
Alzheimer Disease
Location: Boston MA
Sponsor: Boston University Charles River Campus

Sex: All

Age: 50 - 70+

Code: NCT06094192

Recruiting

Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early Alzheimer's Disease.

for
Mild Cognitive Impairment, Early Alzheimer's Disease, AD-MCI
Location: Miami FL
Sponsor: Bernard (Barry) Baumel

Sex: All

Age: 55 - 70+

Code: NCT07512362

Phase2, Recruiting

Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease

for
Alzheimer Disease, Alzheimer Disease, Early Onset
Location: East York, Toronto
Sponsor: Arrowhead Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07221344

Phase1, Phase2, Recruiting

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Music for Pain and Dementia

for
Alzheimer Disease, Dementia, Mild Cognitive Impairment,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 50 - 70+

Code: NCT07602283

Recruiting

Adapting RDAD for DS

for
Down Syndrome (DS), Alzheimer's Disease (AD)
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 0+

Code: NCT07425769

Recruiting

Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

for
Cognitive Impairment, Alzheimer Blood Biomarkers,
Location: Huntsville AL
Sponsor: HudsonAlpha Institute for Biotechnology

Sex: All

Age: 65 - 70+

Code: NCT07146412

Recruiting

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for
Alzheimer Disease, Psychosis
Location: Independence OH, Gilbert AZ, Chino CA
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 55 - 70+

Code: NCT06947941

Phase3, Recruiting

Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

for
Alzheimer Disease
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 60 - 70+

Code: NCT06801639

Recruiting

Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease

for
Alzheimer Disease, Healthy
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18 - 70+

Code: NCT05582200

Recruiting

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

for
Early Alzheimer's Disease
Location: Newton MA, New Haven CT, Queens NY, Toms River NJ,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 50 - 70+

Code: NCT07033494

Phase2, Recruiting

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

for
Psychosis Associated With Alzheimer's Disease
Location: Levis, West Long Branch NJ, Boca Raton FL,
Sponsor: MapLight Therapeutics

Sex: All

Age: 55 - 70+

Code: NCT06887192

Phase2, Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease

for
Alzheimer Disease
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 50+

Code: NCT04576793

Phase2, Recruiting

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease

for
Alzheimer Disease, Chronic Traumatic Encephalopathy
Location: Evanston IL
Sponsor: CereMark Pharma, LLC

Sex: All

Age: 45+

Code: NCT06254469

Phase3, Recruiting

Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers

for
Mild Cognitive Impairment, Alzheimer Disease, Dementia
Location: Greenfield Park
Sponsor: MoCA Clinic and Institute

Sex: All

Age: 55 - 70+

Code: NCT07041450

Recruiting

Olfactory Biopsies

for
Alzheimer Disease, Smell Loss, Smell Dysfunction
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07021040

Recruiting

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

for
Alzheimer Disease and Related Dementias (ADRD),
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 50+

Code: NCT07120347

Recruiting

Speech Pattern Evaluation and Analysis for Knowledge of AD

for
Wisconsin Alzheimer's Disease Research Center,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 40 - 70+

Code: NCT06230783

Recruiting

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

for
Alzheimer Disease, Mild Cognitive Impairment
Location: Charlestown MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 50 - 70+

Code: NCT05904132

Recruiting