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Active & Responsive

Genetic Studies of Early-onset Dementia

for
Dementia, Early Onset, Alzheimer Dementia (AD),
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 35+

Code: NCT04906863

Recruiting
Active & Responsive

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Location: Providence RI, New Haven CT, Quebec, New York NY,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05552157

Phase2, Phase3, Recruiting
Active & Responsive

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

for
Mild Cognitive Impairment, Alzheimer Dementia (AD)
Location: Austin TX
Sponsor: University of Texas at Austin

Sex: All

Age: 18 - 70+

Code: NCT05907343

Recruiting
Active & Responsive

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

for
Amyloidosis, Hereditary, Amyloidosis Cardiac,
Location: New York NY, Cleveland OH, Dallas TX
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 30 - 70+

Code: NCT05489549

Recruiting
Active & Responsive

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for
AAA, AAA - Abdominal Aortic Aneurysm
Location: Boston MA, Staten Island NY, New York NY, Newark NJ,
Sponsor: Endologix

Sex: All

Age: 21+

Code: NCT05064540

Recruiting

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Active & Responsive

Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis

for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM), Amyloidosis,
Location: St Louis MO
Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All

Age: 18 - 70+

Code: NCT07695701

Recruiting
Active & Responsive

Low-Dose Radiotherapy for Alzheimer's Disease

for
Alzheimer Dementia, Dementia, Alzheimer Dementia (AD),
Location: Winter Park FL
Sponsor: Evan Thomas

Sex: All

Age: 50+

Code: NCT07693140

Phase1, Phase2, Recruiting
Active & Responsive

US Benchmarking Clinical Study

for
HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF,
Location: Boston MA
Sponsor: eMyosound SAS

Sex: All

Age: 60+

Code: NCT07215715

Recruiting
Active & Responsive

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

for
Caregivers, Emotions, Emotion Regulation, Stress, Psychological,
Location: Houston TX
Sponsor: Bryan Denny

Sex: All

Age: 18+

Code: NCT05949047

Recruiting
Active & Responsive

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

for
AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 55+

Code: NCT05282550

Phase2, Recruiting
Active & Responsive

CBD for Individuals at Risk for Alzheimer's Disease

for
Mild Cognitive Impairment
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 55 - 70+

Code: NCT05822362

Phase2, Recruiting
New

A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

for
Alzheimer's Disease
Location: Laurelton NY, Toronto, Maitland FL, Santa Ana CA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 55 - 70+

Code: NCT07717411

Phase3, Recruiting
New

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

for
Demyelinating Disorders, MCI, Alzheimer's Disease (AD),
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18 - 70+

Code: NCT06999434

Phase1, Recruiting
New

Biofluid Research on Age-Related or Inherited Neurodegeneration

for
Frontotemporal Degeneration (FTD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07798700

Recruiting
New

Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music

for
Alzheimer's Disease
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 55+

Code: NCT07775625

Recruiting
New

A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

for
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Location: Maitland FL, Naples FL
Sponsor: Alnylam Pharmaceuticals

Sex: All

Age: 40 - 55

Code: NCT07636811

Phase2, Recruiting
New

Microbiome in Aging of Gut and Brain

for
Mild Cognitive Impairment, Alzheimer Disease (AD), Dementia
Location: Tampa FL
Sponsor: University of South Florida

Sex: All

Age: 18+

Code: NCT07799402

Recruiting

A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease

for
Lewy Body Disease, Alzheimer Disease, Healthy
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 50 - 70+

Code: NCT06057909

Recruiting

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

for
Multiple Sclerosis, Alzheimer's Disease
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 70+

Code: NCT02649985

Phase1, Phase2, Recruiting

A 6-Month Study to Evaluate the Safety & Potential Efficacy of Trappsol Cyclo in Patients With Early Alzheimer's Disease

for
Alzheimer's Disease
Location: Neptune NJ, Winter Park FL, Brooksville FL, Marrero LA,
Sponsor: Cyclo Therapeutics, Inc.

Sex: All

Age: 50 - 70+

Code: NCT05607615

Phase2, Recruiting