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Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

for
Stroke, Transient Ischemic Attack (TIA)
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06943586

Recruiting

Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS

for
Antiphospholipid Syndrome, Arterial Thrombosis
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 18+

Code: NCT05646394

Recruiting

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for
Atrial Fibrillation, Stroke, Bleeding
Location: Portland ME, Boston MA, New Haven CT, Lebanon NH,
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT04045665

Phase3, Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke

for
Ischemic Stroke, CYP2C19 Polymorphism
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 18+

Code: NCT06292117

Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

for
Cardiac Allograft Vasculopathy, Heart Transplant
Location: Ottawa, Toronto, Vancouver
Sponsor: Ottawa Heart Institute Research Corporation

Sex: All

Age: 18+

Code: NCT04770012

Phase3, Recruiting

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Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study

for
Coronary Artery Disease
Location: Jacksonville FL
Sponsor: University of Florida

Sex: All

Age: 18+

Code: NCT06821191

Recruiting

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

for
Coronary Arterial Disease (CAD)
Location: Jacksonville FL
Sponsor: University of Florida

Sex: All

Age: 18+

Code: NCT07225842

Recruiting

Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)

for
Coronary Arterial Disease (CAD),
Location: Jacksonville FL
Sponsor: University of Florida

Sex: All

Age: 18+

Code: NCT07025148

Recruiting

Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia

for
Baseline Thrombocytopenia
Location: Dallas TX
Sponsor: Methodist Health System

Sex: All

Age: 18+

Code: NCT06223607

Recruiting

Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors

for
Coronary Artery Disease
Location: Jacksonville FL
Sponsor: University of Florida

Sex: All

Age: 18 - 70+

Code: NCT06691191

Recruiting

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

for
Stroke, Intracranial Atherosclerotic Stenosis (ICAS)
Location: New Haven CT, Manhasset NY, Washington D.C. DC,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05907629

Recruiting

Differential EFfects of Dual antIplatelet and Dual aNtithrombotic thErapy on Hemostasis in Chronic Coronary Syndrome Patients

for
Thrombosis, Myocardial Infarction
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 55+

Code: NCT05116995

Recruiting

Mechanisms of Alcohol Sensitivity in AERD

for
Aspirin-Sensitive Asthma With Nasal Polyps, Samter's Syndrome
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 21+

Code: NCT03441438

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II

for
Platelet Aggregation, Type 2 Diabetes, Aspirin,
Location: Montreal
Sponsor: Montreal Heart Institute

Sex: All

Age: 18+

Code: NCT05702463

Phase1, Recruiting

The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity

for
Venous Thromboembolism, Postpartum Period, Aspirin,
Location: Calgary
Sponsor: University of Calgary

Sex: Female

Age: 18+

Code: NCT06494878

Phase3, Recruiting

Reversal of the Antiplatelet Effects of Ticagrelor in Combination With Aspirin, Using Normal Platelets

for
Ticagrelor, Aspirin, Platelet Dysfunction Due to Drugs,
Location: Hamilton
Sponsor: Hamilton Health Sciences Corporation

Sex: All

Age: 18+

Code: NCT03005704

Recruiting