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Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

for
Chronic Graft Versus Host Disease
Location: Atlanta GA
Sponsor: Northside Hospital, Inc.

Sex: All

Age: 18+

Code: NCT06046248

Phase2, Recruiting

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

for
Graft-versus-leukemia, Graft vs Host Disease, Graft Rejection
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 7 - 70+

Code: NCT00106925

Recruiting

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

for
Chronic Graft Versus Host Disease
Location: Boston MA, New York NY, Tampa FL, Seattle WA, Duarte CA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT05996627

Phase2, Recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease

for
Steroid Refractory GVHD
Location: Columbus OH, Atlanta GA, Cincinnati OH, St Louis MO,
Sponsor: ReAlta Life Sciences, Inc.

Sex: All

Age: 12+

Code: NCT06343792

Phase2, Recruiting

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

for
Chronic Graft-versus-host-disease
Location: Boston MA, Miami FL, Pittsburgh PA, Columbus OH,
Sponsor: Syndax Pharmaceuticals

Sex: All

Age: 2+

Code: NCT04710576

Phase2, Recruiting

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Post-Transplant Cyclophosphamide, Bortezomib and Abatacept for the Prevention of Graft-versus-Host-Disease (GvHD)

for
Graft-versus-host Disease
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: All

Age: 14 - 70+

Code: NCT05289167

Phase1, Phase2, Recruiting

Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease

for
Chronic Graft Versus Host Disease,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07535008

Recruiting

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

for
Graft-versus-Host Disease (GVHD), Hematologic Malignancies,
Location: Hershey PA
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 18+

Code: NCT06926595

Phase2, Recruiting

Evaluation of Belumosudil Whole Tablets vs. Crushed Tablets Pharmacokinetics in Patients Suffering From Chronic GvHD

for
Chronic Graft Versus Host Disease
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07127926

Phase1, Recruiting

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

for
Graft Vs Host Disease
Location: Boston MA, Rochester NY, Atlanta GA, Chicago IL
Sponsor: Boston Children's Hospital

Sex: All

Age: 2+

Code: NCT04380740

Phase2, Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

for
Chronic Graft-versus-host-disease
Location: New York NY, Washington D.C. DC, Charlotte NC,
Sponsor: Incyte Corporation

Sex: All

Age: 2 - 17

Code: NCT07124078

Phase2, Recruiting

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

for
T-cell Lymphoma, Graft Versus Host Disease, Lymphoma, T-Cell,
Location: Columbus OH
Sponsor: Jonathan Brammer

Sex: All

Age: 18+

Code: NCT07356245

Phase2, Recruiting

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

for
GVHD, Hematopoietic Cell Transplantation (HCT),
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18 - 70+

Code: NCT07302776

Phase1, Recruiting

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

for
Bone Marrow Transplant Complications, Graft-versus-Host Disease
Location: Boston MA, Miami FL
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06910969

Recruiting

Ex Vivo-Expanded Regulatory T Cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD

for
Graft Versus Host Disease (cGvHD)
Location: Boston MA
Sponsor: Leslie Kean

Sex: All

Age: 2+

Code: NCT06991361

Phase1, Recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

for
GVHD,Acute, Acute Leukemia, Myelodysplastic Syndromes,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 60

Code: NCT06315309

Phase2, Recruiting

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

for
GVHD,Acute
Location: Detroit MI
Sponsor: Henry Ford Health System

Sex: All

Age: 18 - 70+

Code: NCT05718791

Recruiting

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

for
Hematological Malignancies, Graft-versus-Host Disease (GVHD)
Location: Omaha NE
Sponsor: University of Nebraska

Sex: All

Age: 60+

Code: NCT06799195

Phase2, Recruiting

Axatilimab for Sclerotic Chronic Graft-versus-Host Disease

for
Chronic Graft Versus Host Disease
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT07011810

Phase2, Recruiting

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

for
Graft Vs Host Disease, Vitamin A Deficiency,
Location: Buffalo NY, Tampa FL, Columbus OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 18+

Code: NCT06450925

Phase2, Recruiting