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A Study to Evaluate the Safety and Efficacy of Oral APL-1202 in Combination With Tislelizumab Compared to Tislelizumab Alone as Neoadjuvant Therapy in Patients With Muscle Invasive Bladder Cancer

for
Muscle Invasive Bladder Cancer
Location: New York NY
Sponsor: Jiangsu Yahong Meditech Co., Ltd aka Asieris

Sex: All

Age: 18+

Code: NCT04813107

Phase1, Phase2, Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

for
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer,
Location: Boston MA, Lebanon NH, New York NY, New Brunswick NJ,
Sponsor: Iambic Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06253871

Phase1, Recruiting

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

for
Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05312671

Phase2, Recruiting

Measuring Surgical Recovery After Radical Cystectomy

for
Bladder Cancer
Location: Baltimore MD, Rochester NY, Atlanta GA, Chicago IL,
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03193970

Recruiting

PLZ4-Coated Paclitaxel-Loaded Micelles for the Treatment of Patients With Recurrent or Refractory Non-Muscle Invasive Bladder Cancer

for
Recurrent Non-Muscle Invasive Bladder Carcinoma,
Location: Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 18+

Code: NCT06173349

Phase1, Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for
Advanced Solid Tumor, Advanced Malignant Neoplasm,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: PMV Pharmaceuticals, Inc

Sex: All

Age: 12+

Code: NCT04585750

Phase1, Phase2, Recruiting

Metformin and Simvastatin Use in Bladder Cancer

for
Bladder Cancer
Location: London
Sponsor: London Health Sciences Centre

Sex: All

Age: 18 - 70+

Code: NCT02360618

Phase2, Recruiting

A Study of T3011 in Patients With BCG-Unresponsive NMIBC or BCG-Exposed, Chemotherapy-Unresponsive NMIBC

for
Nonmuscle-invasive Bladder Cancer
Location: New Brunswick NJ, Myrtle Beach SC, Pittsburgh PA,
Sponsor: ImmVira Pharma Co. Ltd

Sex: All

Age: 18+

Code: NCT06971614

Phase2, Recruiting

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

for
Invasive Ductal Breast Carcinoma,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05837767

Recruiting

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

for
Urothelial Bladder Cancer, Muscle-Invasive Bladder Cancer
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT06335667

Recruiting

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for
Non-muscle-invasive Bladder Cancer
Location: Boston MA, Annapolis MD, Myrtle Beach SC,
Sponsor: SURGE Therapeutics

Sex: All

Age: 18+

Code: NCT05710848

Phase1, Phase2, Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for
Bladder Adenocarcinoma, Bladder Clear Cell Adenocarcinoma,
Location: Peabody MA, Burlington MA, Commack NY, Uniondale NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03866382

Phase2, Recruiting

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

for
Bladder Cancer, Urinary Tract Infection
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 18+

Code: NCT06689176

Recruiting

Metabolism Evaluation Through Resting Indirect Calorimetry in Bladder Cancer (METRICS)

for
Bladder Cancer
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT06721260

Recruiting

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

for
Small Cell Carcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06161532

Phase2, Recruiting

Patient-Derived Xenografts to Reduce Cancer Health Disparities

for
Bladder Carcinoma, Gastric Carcinoma,
Location: Orange CA, Sacramento CA
Sponsor: University of California, Davis

Sex: All

Age: 21 - 70+

Code: NCT04410302

Recruiting

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy

for
Urothelial Carcinoma Bladder
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 18 - 70+

Code: NCT06184516

Phase2, Recruiting

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

for
Muscle-Invasive Bladder Carcinoma, Tumor
Location: Los Angeles CA
Sponsor: Leslie Ballas

Sex: All

Age: 18+

Code: NCT06417190

Phase2, Recruiting

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

for
Small Cell Carcinoma of the Bladder,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT06228066

Phase2, Recruiting

Adaptive RADiation Therapy With Concurrent Sacituzumab Govitecan (SG) for Muscle Invasive Bladder Cancer

for
Localized Muscle Invasive Bladder Urothelial Carcinoma,
Location: Cleveland OH
Sponsor: Shilpa Gupta, MD

Sex: All

Age: 18+

Code: NCT05833867

Phase1, Recruiting