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Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase1, Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Scarborough ME, Worcester MA, Hartford CT, Norwalk CT,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & Responsive

B.Brilliant Revelation Comparision Study

for
Breast Cancer Screening
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: Female

Age: 18+

Code: NCT07067788

Recruiting
Active & Responsive

Increasing Germline Genetic Testing for Patients With Cancer

for
Hereditary Pancreatic Cancer, Conditions or Focus of Study,
Location: Danville PA, Durham NC, Salisbury NC, Orlando FL,
Sponsor: Josh Peterson

Sex: All

Age: 0+

Code: NCT07307664

Recruiting
Active & Responsive

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for
Breast Cancer Screening, Breast Carcinoma in Situ,
Location: New York NY, Miami FL, Birmingham AL, Chicago IL,
Sponsor: University of California, San Francisco

Sex: Female

Age: 30 - 70+

Code: NCT02620852

Recruiting

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Active & ResponsiveNew

A Study to Identify Breast Cancer (IDBC)

for
Breast Cancer Female
Location: Calgary
Sponsor: Syantra Inc.

Sex: Female

Age: 30 - 70+

Code: NCT04495244

Recruiting
Active & ResponsiveNew

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Upland CA, Irvine CA, Lancaster CA, Duarte CA,
Sponsor: City of Hope Medical Center

Sex: Female

Age: 18+

Code: NCT07741968

Recruiting
Active & ResponsiveNew

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)

for
Triple Negative Breast Cancer (TNBC),
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT07743190

Phase2, Recruiting
Active & ResponsiveNew

Breast Cancer Plasma Adjuvant Intra-operative Treatment (Breast Cancer PAINT)

for
Breast Cancer
Location: Montreal
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: Female

Age: 18+

Code: NCT06222788

Recruiting
Active & ResponsiveNew

Tai Chi for Reducing Aromatase Inhibitor-Induced Arthralgia

for
Hormone Receptor Positive Breast Carcinoma, Postmenopausal,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: Female

Age: 18+

Code: NCT07737951

Recruiting
Active & Responsive

Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs

for
Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis),
Location: Jamaica NY, New York NY, Brooklyn NY, Staten Island NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06559059

Recruiting
Active & Responsive

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

for
Breast Cancer Female
Location: New Haven CT, Newport News VA, Richmond VA, Fairfax VA,
Sponsor: University of Virginia

Sex: Female

Age: 65+

Code: NCT06507618

Phase3, Recruiting
Active & Responsive

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

for
Metastatic Breast Cancer
Location: Brewer ME, Augusta ME, Weymouth MA, Boston MA,
Sponsor: American Society of Clinical Oncology

Sex: All

Age: 60+

Code: NCT06377852

Phase3, Recruiting
Active & Responsive

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer,
Location: New Haven CT, Lake Success NY, New York NY, Fairfax VA,
Sponsor: Cogent Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07361562

Phase1, Recruiting
Active & Responsive

Breast Cancer, Reasoning, and Activity Intervention

for
Breast Cancer, Breast Neoplasms,
Location: Phoenix AZ
Sponsor: Mayo Clinic

Sex: Female

Age: 50+

Code: NCT04816006

Recruiting
Active & Responsive

Biennial CEM in Women With a Personal History of Breast Cancer

for
Breast Cancer, Breast Neoplasms, Breast Cancer Female,
Location: Monroeville PA, West Mifflin PA, Pittsburgh PA,
Sponsor: Wendie Berg

Sex: Female

Age: 30 - 70+

Code: NCT06105749

Recruiting
Active & Responsive

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for
Solid Tumor, Adult, Colorectal Cancer,
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.

Sex: All

Age: 18+

Code: NCT04981119

Recruiting
Active & Responsive

Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery

for
Breast Cancer
Location: The Bronx NY
Sponsor: Albert Einstein College of Medicine

Sex: Female

Age: 18 - 70+

Code: NCT06524895

Recruiting
Active & Responsive

Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer

for
Breast Cancer Females
Location: Toronto
Sponsor: University of Toronto

Sex: Female

Age: 0+

Code: NCT06776458

Recruiting
Active & Responsive

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

for
HER2-positive Metastatic Breast Cancer
Location: Westerly RI, Waterford CT, Guilford CT, Glastonbury CT,
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06551116

Recruiting