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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for
Breast Neoplasms, Neoplasm Metastasis
Location: Summit NJ, Philadelphia PA, Cherry Hill NJ, Sewell NJ,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07174336

Phase3, Recruiting

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

for
BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 25+

Code: NCT05420064

Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for
Breast Neoplasms
Location: Westbrook ME, Burlington MA, New York NY,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07173751

Phase3, Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for
Ovarian Neoplasms, Breast Neoplasms,
Location: Boston MA, New York NY, Philadelphia PA, Glen Burnie MD,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213791

Phase1, Recruiting

Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

for
Breast Carcinoma
Location: Jacksonville FL, Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 18 - 70+

Code: NCT07207564

Recruiting

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Study of How People Make Decisions About Prostate Cancer Risk

for
BRCA1/2, Geneitic Testing
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male

Age: 45 - 70

Code: NCT07197723

Recruiting

A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

for
Ovarian Neoplasms, Breast Neoplasms
Location: Boston MA, Lake Success NY, Morristown NJ, Toronto,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT04641247

Phase2, Recruiting

Intratumoral N17350 in Advanced Solid Tumors

for
Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative,
Location: Buffalo NY
Sponsor: Onchilles Pharma Inc

Sex: All

Age: 18+

Code: NCT07339176

Phase1, Phase2, Recruiting

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

for
Breast Neoplasms
Location: Shirley NY, Indianapolis IN, Nashville TN, Houston TX
Sponsor: Eli Lilly and Company

Sex: Female

Age: 18+

Code: NCT07287098

Phase2, Recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

for
Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency),
Location: New Haven CT, New York NY, Houston TX, Sacramento CA
Sponsor: Duke Street Bio Ltd

Sex: All

Age: 18+

Code: NCT06458712

Phase1, Recruiting

Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction

for
Breast Neoplasm
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18 - 70+

Code: NCT06294574

Recruiting

Diet Synergy in Muscle Protein Synthesis

for
Muscle Protein Synthetic Response to Protein,
Location: Urbana IL
Sponsor: University of Illinois at Urbana-Champaign

Sex: All

Age: 19 - 40

Code: NCT07367854

Recruiting

The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI

for
Breast Neoplasm Female, Early Detection of Cancer,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: Female

Age: 18 - 70+

Code: NCT06892275

Recruiting

Observational Study of Iris Tumors

for
Iris Tumor
Location: Portland OR
Sponsor: Oregon Health and Science University

Sex: All

Age: 18+

Code: NCT03809585

Recruiting

Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk

for
HER2-Positive Breast Carcinoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: Female

Age: 0+

Code: NCT06557057

Recruiting

The Vanguard Study: Testing a New Way to Screen for Cancer

for
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma,
Location: Portsmouth VA, Norfolk VA, Bethesda MD, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 45 - 70+

Code: NCT06995898

Recruiting

Atacicept in Multiple Glomerular Diseases

for
pMN, IgAN, Nephrotic Syndrome, MCD, FSGS
Location: Brisbane CA
Sponsor: Vera Therapeutics, Inc.

Sex: All

Age: 2+

Code: NCT06983028

Phase2, Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for
Breast Neoplasms
Location: Boston MA, Sherbrooke, Westbury NY, White Plains NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT06926868

Phase2, Phase3, Recruiting

Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer

for
Breast Carcinoma
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 30 - 70+

Code: NCT07076147

Recruiting

A Post-treatment Supportive Service Program for the Transition Into Survivorship for Black Women Breast Cancer Survivors in Western New York

for
Breast Carcinoma
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06833255

Recruiting