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Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for
Non-Small Cell Lung Cancer,
Location: Montreal, Fairfax VA, Durham NC, Toronto,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT05005403

Phase1, Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

for
Metabolic Disease, Obesity, Li-Fraumeni Syndrome,
Location: Washington D.C. DC, Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 1 - 70+

Code: NCT01143454

Recruiting

Clinical and Genetic Studies of Li-Fraumeni Syndrome

for
Li-Fraumeni Syndrome, Neoplasms, Tp53 Mutations
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0+

Code: NCT01443468

Recruiting

Interactive Design of Patient-Specific Molds for Tissue Shaping

for
Mastectomy
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06711965

Recruiting

A Study of Genetic Based Chemotherapy Dosing for Breast Cancer Patients

for
Breast Neoplasms
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: Female

Age: 18+

Code: NCT01740271

Phase2, Recruiting

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A Trial Evaluating the Efficacy of Ivonescimab in Metastatic Endocrine Refractory HR-positive HER2-negative or Triple Negative Invasive Lobular Carcinoma

for
Metastatic Endocrine Refractory,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07229417

Phase2, Recruiting

Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling

for
Li-Fraumeni Syndrome
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT05126810

Recruiting

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

for
Cutaneous Squamous Cell Carcinoma,
Location: Uniondale NY, New York NY, Middletown NJ, Montvale NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05859074

Phase1, Recruiting

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

for
Solid Tumours, Sarcoma, HNSCC, Non Small Cell Lung Cancer,
Location: Houston TX, Beverly Hills CA, Santa Monica CA
Sponsor: Epkin

Sex: All

Age: 18+

Code: NCT06789172

Phase1, Recruiting

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress

for
Li-Fraumeni Syndrome, TP53 Gene Mutation,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 0+

Code: NCT04541654

Recruiting

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

for
Vulvar Adenocarcinoma, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Fairfax VA, Grand Rapids MI, Irving TX
Sponsor: Avacta Life Sciences Ltd

Sex: All

Age: 18+

Code: NCT07454642

Phase1, Recruiting

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

for
Lung Cancer (NSCLC), Geriatric Assessment,
Location: Boston MA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 65+

Code: NCT06987890

Recruiting

[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications

for
Colorectal Cancer, Epithelial Ovarian Cancer, Gastric Cancer,
Location: Dallas TX
Sponsor: Blue Earth Diagnostics

Sex: All

Age: 18 - 70+

Code: NCT07432633

Phase1, Phase2, Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for
Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07285044

Phase2, Recruiting

Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy

for
Metastatic HER2-Negative Breast Carcinoma,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05770531

Phase2, Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

for
Advanced Anal Carcinoma, Advanced Biliary Tract Carcinoma,
Location: Jacksonville FL, Grand Forks ND
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05969860

Phase2, Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for
Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma,
Location: Lewiston ME, East Brunswick NJ, Philadelphia PA,
Sponsor: Guardant Health, Inc.

Sex: All

Age: 18+

Code: NCT05059444

Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Montreal, Fairfax VA, Toronto, Cleveland OH, Detroit MI,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase1, Recruiting

Prospective Analysis of EnVisio Spatial Intelligence for Soft Tissue Localization and Guided Surgical Excision

for
Tumors, Breast
Location: Winter Garden FL
Sponsor: Elucent Medical

Sex: Female

Age: 18+

Code: NCT06572410

Recruiting

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

for
Ovarian Neoplasms, Endometrial Neoplasms,
Location: Mineola NY, New York NY, Columbus OH, Grand Rapids MI,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06400472

Phase1, Recruiting