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Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

for
Obesity and Obesity-related Medical Conditions, Diabetes,
Location: Columbia MO
Sponsor: Bettina Mittendorfer

Sex: All

Age: 18 - 70+

Code: NCT07083557

Recruiting

Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease

for
Chronic Kidney Disease(CKD), Type 1 Diabetes (T1D)
Location: Cleveland OH
Sponsor: The Cleveland Clinic

Sex: All

Age: 18 - 65

Code: NCT06694558

Recruiting

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for
Chronic Kidney Disease (CKD)
Location: Philadelphia PA, Baltimore MD, Chicago IL,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18 - 70

Code: NCT05106387

Recruiting

Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

for
Chronic Kidney Disease (CKD)
Location: Baltimore MD, Aurora CO
Sponsor: VA Office of Research and Development

Sex: All

Age: 55+

Code: NCT06607913

Recruiting

A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)

for
Chronic Kidney Disease; Iron Deficiency Anemia
Location: The Bronx NY, Morgantown WV, Akron OH, Kansas City MO
Sponsor: AMAG Pharmaceuticals, Inc.

Sex: All

Age: 2 - 17

Code: NCT03619850

Phase3, Recruiting

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Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

for
Chronic Kidney Diseases
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06927024

Recruiting

Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

for
Chronic Kidney Diseases, Kidney Transplant
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06752577

Recruiting

A Study to Investigate the Safety, Tolerability, and Preliminary Efficacy With AION-301 Administered by Intravenous Infusion Compared With Placebo Administered by Intravenous Infusion Investigational Intervention in Participants Aged 35 to 75 Years of Age With Chronic Kidney Disease (CKD)

for
Chronic Kidney Disease Stage 3
Location: Miami FL
Sponsor: AION Healthspan, Inc.

Sex: All

Age: 35 - 70+

Code: NCT06721143

Phase1, Phase2, Recruiting

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

for
Diabetic Nephropathy Type 2 - Uncontrolled,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT05692388

Recruiting

Chronic Kidney Disease-Education (CKD-EDU)

for
Chronic Kidney Diseases
Location: Canandaigua NY, Hornell NY, Rochester NY, Brockport NY
Sponsor: University of Rochester

Sex: All

Age: 70+

Code: NCT06410144

Recruiting

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

for
Hypertension, High Blood Pressure, Diabetes,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT05321368

Recruiting

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

for
Chronic Kidney Disease
Location: Decatur GA, Atlanta GA
Sponsor: Emory University

Sex: All

Age: 40 - 70+

Code: NCT05928936

Phase2, Recruiting

Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis

for
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18+

Code: NCT06913647

Phase2, Recruiting
New

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

for
Type 2 Diabetes Mellitus,
Location: Raleigh NC, Miami Lakes FL, Ocoee FL, Gaffney SC,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07662135

Phase3, Recruiting

Patient-driven Management of BP in CKD

for
Chronic Kidney Disease
Location: Iowa City IA
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT05546099

Phase3, Recruiting

Fluid Intake After Hemodialysis

for
Chronic Kidney Disease Requiring Chronic Dialysis,
Location: London
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All

Age: 18+

Code: NCT04721652

Recruiting

Transforming Hemodialysis-Related Vascular Access Education

for
Chronic Kidney Disease, Hemodialysis Vascular Access
Location: Philadelphia PA, Baltimore MD, Chapel Hill NC
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT05997875

Recruiting

Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease

for
Chronic Kidney Disease Predialysis
Location: Washington D.C. DC
Sponsor: VA Office of Research and Development

Sex: All

Age: 50 - 70+

Code: NCT04397159

Recruiting

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

for
Secondary Hyperparathyroidism, Chronic Kidney Disease
Location: Philadelphia PA, Cleveland OH, Kansas City MO,
Sponsor: Amgen

Sex: All

Age: 0 - 18

Code: NCT03633708

Phase3, Recruiting

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

for
Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease
Location: Moncton, Quebec, Chicoutimi, Trois-Rivieres, Montreal,
Sponsor: Eli Lilly and Company

Sex: All

Age: 50+

Code: NCT07241390

Phase3, Recruiting