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Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial

for
Major Depressive Disorder
Location: Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 60+

Code: NCT06626152

Phase2, Recruiting

Cognitive Dysfunction in the Addictions Study - Project 4 (P4)

for
Major Depressive Disorder, Alcohol Use Disorder
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 59

Code: NCT06299787

Recruiting

Auditory MMN EEG in TRD in Response to Ketamine

for
Treatment-resistant Depression (TRD)
Location: Toronto
Sponsor: Unity Health Toronto

Sex: All

Age: 18 - 65

Code: NCT05464264

Recruiting

Inflammatory Markers and Cognitive Function in Major Depression

for
Major Depression
Location: Montreal
Sponsor: Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal

Sex: All

Age: 20 - 50

Code: NCT01391221

Recruiting

Augmenting Mental Health Support Through a Supportive Text Messaging Program

for
Major Depressive Disorder, Generalized Anxiety Disorder,
Location: Halifax
Sponsor: Vincent Agyapong

Sex: All

Age: 16 - 65

Code: NCT05411302

Recruiting

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Effect of Antidepressants on White Matter Structure

for
Major Depression
Location: Montreal
Sponsor: Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal

Sex: All

Age: 18 - 55

Code: NCT01492621

Recruiting

Mindful Waiting Room

for
Anxiety State, Depressive State, Pain, Nausea, Fatigue, Cancer
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05433636

Recruiting

Personalized Indications for CBT and Antidepressants in Treating Depression

for
Major Depressive Disorder, Persistent Depressive Disorder
Location: Halifax
Sponsor: Nova Scotia Health Authority

Sex: All

Age: 18+

Code: NCT02752542

Recruiting

Pilot RCT to Test Effectiveness of the ACE4 (Activity Challenge- 4 Areas) for Depression and Anxiety

for
Anxiety Disorder; Mixed With Depression (Mild)
Location: Kingston
Sponsor: Queen's University

Sex: All

Age: 18 - 65

Code: NCT02538549

Recruiting

Accelerated TBS in Late Life Depression

for
Treatment Resistant Depression
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 60+

Code: NCT05119699

Recruiting

Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas

for
Chronic Subdural Hematoma, Epilepsy; Seizure,
Location: Sherbrooke
Sponsor: Université de Sherbrooke

Sex: All

Age: 18+

Code: NCT04759196

Recruiting

Brain Insulin Resistance in Mood Disorders

for
Major Depressive Disorder, Bipolar Disorder, Anhedonia,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18 - 60

Code: NCT03915613

Phase1, Phase2, Recruiting

Mood And Kids diEt (MAKE-It) Pilot Trial

for
Depression - Major Depressive Disorder, Adolescent
Location: Toronto
Sponsor: The Hospital for Sick Children

Sex: All

Age: 11 - 17

Code: NCT06716034

Recruiting

Efficacy and Safety Study of Desvenlafaxine in the Treatment of Vascular Depression

for
Vascular Depression
Location: Windsor
Sponsor: Hotel-Dieu Grace Healthcare

Sex: All

Age: 60 - 70+

Code: NCT01974934

Recruiting

Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression

for
Cannabis Use, Major Depressive Disorder, Cognitive Impairment
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 55

Code: NCT04935619

Recruiting

Postpartum Screening for Anxiety and Comorbid Conditions

for
Postpartum Anxiety, Postpartum Depression, Postpartum Disorder,
Location: Vancouver
Sponsor: University of British Columbia

Sex: Female

Age: 19+

Code: NCT06242717

Recruiting

Prediction of Antidepressant Treatment Response Using Machine Learning Classification Analysis

for
Major Depressive Disorder
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 20 - 55

Code: NCT02330679

Recruiting

Biomarkers of Theta Burst Stimulation in Major Depressive Disorder

for
Depressive Disorder, Treatment-Resistant
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 18 - 65

Code: NCT03626181

Recruiting

Ketogenic Diet Therapy Major Depressive Disorder

for
Major Depressive Disorder
Location: Kingston
Sponsor: Queen's University

Sex: All

Age: 18 - 55

Code: NCT05558995

Recruiting

Pilot Study of the Safety and Tolerability of L-DLPFC iTBS rTMS for MDD in MS

for
Multiple Sclerosis, Major Depressive Disorder
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18 - 70

Code: NCT04621708

Recruiting