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Active & Responsive

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

for
Depressive Symptoms, Depression, Alzheimer Disease,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18 - 70+

Code: NCT04123314

Early_phase1, Recruiting
Active & Responsive

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

for
Depressive Disorder, Major
Location: Boston MA, Watertown MA, Foxborough MA, Levis,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07412756

Phase3, Recruiting
Active & Responsive

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

for
Anxiety Disorders, Generalized Anxiety Disorder,
Location: Washington D.C. DC
Sponsor: Georgetown University

Sex: All

Age: 18 - 65

Code: NCT07028216

Recruiting
Active & Responsive

Brief Skills for Safer Living (Brief-SfSL)

for
Suicide Prevention, Suicide, Suicide and Self-harm, Depression,
Location: St. John's, Grand Falls-Windsor, Corner Brook,
Sponsor: Unity Health Toronto

Sex: All

Age: 18+

Code: NCT06571916

Recruiting
Active & Responsive

Test of Target Engagement of Ambiguity Aversion

for
Intolerance of Uncertainty, Anxiety,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 25 - 60

Code: NCT06962527

Recruiting

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Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Boston MA, Nashua NH, New York NY, Woodbury NY,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

Defining Neurobiological Links Between Substance Use and Mental Illness

for
Major Depressive Disorder, Substance Use Disorder,
Location: Baltimore MD
Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All

Age: 18 - 60

Code: NCT05538910

Recruiting
Active & Responsive

Sleep Mechanisms Of Regulating Emotions

for
Insomnia, Depression
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18 - 65

Code: NCT06373718

Recruiting
Active & Responsive

rTMS for Depression in Young Adults With Autism

for
Autism Spectrum Disorder, Major Depressive Disorder
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 16 - 35

Code: NCT04972136

Recruiting
Active & Responsive

Intravenous Ketamine for Treatment-Resistant Depression

for
Depressive Disorder, Treatment-Resistant,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 65

Code: NCT06668571

Phase2, Recruiting
Active & Responsive

Theta-Burst Stimulation for Bipolar Depression

for
Bipolar Depression, Bipolar Disorder,
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 18 - 65

Code: NCT06370988

Recruiting
Active & Responsive

Positive Processes and Transition to Health (PATH)

for
Posttraumatic Stress Disorder, Major Depressive Disorder
Location: Newark DE, Cleveland OH, Seattle WA
Sponsor: Case Western Reserve University

Sex: All

Age: 18 - 65

Code: NCT06093906

Recruiting
Active & Responsive

An Innovative Master Platform for Clinical Trials in Mood Disorders

for
Mood Disorders, Depressive Disorder,
Location: Halifax, Ottawa, Kingston, Whitby, Toronto, Hamilton,
Sponsor: St. Joseph's Healthcare Hamilton

Sex: All

Age: 16+

Code: NCT06408012

Recruiting
Active & Responsive

Regulation of Affect and Physiology in Depression

for
Major Depressive Disorder
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18 - 27

Code: NCT06345859

Phase2, Recruiting
Active & Responsive

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

for
Multiple Sclerosis, Major Depressive Disorder
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 64

Code: NCT05051618

Recruiting
Active & Responsive

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for
Treatment Resistant Depression
Location: Boston MA, New York NY, New Brunswick NJ,
Sponsor: Abbott Medical Devices

Sex: All

Age: 22 - 70

Code: NCT06423430

Recruiting
Active & Responsive

Equipping Patients Using Interventions for Pain and Depression

for
Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT06500780

Recruiting
Active & Responsive

SAINT in Postpartum Depression (PPD)

for
Postpartum Depression (PPD)
Location: Worcester MA, New York NY, Charleston SC, Austin TX
Sponsor: Magnus Medical

Sex: Female

Age: 18 - 45

Code: NCT07210255

Recruiting
Active & Responsive

Parent Encouragement And Coaching of Happiness in Youth

for
Depression, Parent-Child Relations
Location: Pittsburgh PA
Sponsor: University of Pittsburgh

Sex: All

Age: 4 - 70+

Code: NCT06725160

Recruiting
Active & Responsive

Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction

for
Depression, Depression During the Menopausal Transition,
Location: San Diego CA
Sponsor: University of California, San Diego

Sex: Female

Age: 45 - 70+

Code: NCT06678880

Recruiting