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Network Effects of Therapeutic Deep Brain Stimulation

for
Intractable Epilepsy
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT05600738

Recruiting

Pilot Trial to Evaluate The Effect of Oral Methylprednisolone on Seizure Frequency in Children With Epilepsy

for
Intractable Epilepsy, Convulsive Seizures
Location: New Orleans LA
Sponsor: Louisiana State University Health Sciences Center in New Orleans

Sex: All

Age: 2 - 18

Code: NCT04219995

Phase1, Phase2, Recruiting

Voronistat in Pediatric Patients With Drug Resistant Epilepsy

for
Refractory Epilepsy
Location: Calgary
Sponsor: University of Calgary

Sex: All

Age: 2 - 17

Code: NCT03894826

Phase2, Recruiting

Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation

for
Intractable Epilepsy
Location: Houston TX
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 0 - 18

Code: NCT02846272

Recruiting

Exercise for Brain Regeneration in Epilepsy

for
Temporal Lobe Epilepsy
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18 - 65

Code: NCT05179083

Phase1, Recruiting

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Modulating Movement Intention Via Cortical Stimulation

for
Seizures, Seizure Disorder, Psychogenic Movement Disorder
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 65

Code: NCT03233399

Recruiting

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

for
Delirium, Epileptics, Neuroleptics
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05431595

Phase2, Phase3, Recruiting

A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures

for
Functional Seizures, Convulsion, Non-Epileptic
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 11 - 18

Code: NCT05819268

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

for
AMPD3, OMIM*102772, AMP Deaminase Deficiency,
Location: Bethesda MD
Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All

Age: 0 - 70+

Code: NCT06092346

Recruiting

SLC6A1-NDD Prospective Longitudinal Natural History Study

for
SLC6A1 Neurodevelopmental Disorder (NDD),
Location: New York NY
Sponsor: UCB Biopharma SRL

Sex: All

Age: 0 - 17

Code: NCT07531511

Recruiting

Retraining and Control Therapy (ReACT) R33 Phase

for
Convulsion, Non-Epileptic
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 11 - 18

Code: NCT06007053

Recruiting

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

for
Epileptic Encephalopathy, SCN2A Encephalopathy
Location: Philadelphia PA, Cincinnati OH, Chicago IL, Memphis TN,
Sponsor: Praxis Precision Medicines

Sex: All

Age: 0 - 18

Code: NCT07019922

Phase3, Recruiting

Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND

for
Functional Neurological Disorder, Convulsion, Non-Epileptic,
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 8 - 70+

Code: NCT06362161

Recruiting

Retraining and Control Therapy (ReACT)- Adults

for
Convulsion, Non-Epileptic
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 19+

Code: NCT06570954

Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

for
Frontotemporal Degeneration(FTD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT04715399

Recruiting

Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age

for
Dravet Syndrome (DS), Children Under 2 Years
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 1 - 2

Code: NCT06598449

Recruiting

Amplitude Titration to Improve ECT Clinical Outcomes

for
Depression, ECT, Cognitive Change
Location: Albuquerque NM
Sponsor: University of New Mexico

Sex: All

Age: 50+

Code: NCT05699226

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

for
Dravet Syndrome
Location: Durham NC, Miami FL, Columbus OH, Ann Arbor MI,
Sponsor: Encoded Therapeutics

Sex: All

Age: 0 - 17

Code: NCT05419492

Phase1, Phase2, Recruiting

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

for
Hyper IgE Syndrome From STAT3 Mutation, Job s Syndrome, HIES,
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 12 - 70+

Code: NCT07262983

Phase1, Recruiting

18F-mFBG Cardiac Uptake With Lewy Body Dementia

for
Parkinson Disease (PD), Lewy Body Dementia (LBD)
Location: Houston TX
Sponsor: Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)

Sex: All

Age: 18+

Code: NCT07176286

Phase2, Recruiting