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A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

for
Cancer, Immunotherapy, PD-1, PD-L1, Immune Checkpoint Therapy
Location: Norwich CT, Rock Hill SC, Dublin GA
Sponsor: Oxford Biodynamics Inc.

Sex: All

Age: 18+

Code: NCT06635954

Recruiting

Prospective Observational Cohort Study of Transplant and Cell Therapy Candidates and Recipients to Assess Social Determinants of Health

for
Transplant and Cell Therapy
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06431347

Recruiting

Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?

for
Sepsis, Systemic Inflammatory Response Syndrome,
Location: Lansing MI
Sponsor: Michigan State University

Sex: All

Age: 18+

Code: NCT01904188

Recruiting

Looking at Cognitive and Brain Changes in People With Lymphoma Receiving CAR-T Therapy

for
Lymphoma Receiving CAR-T Therapy
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04107285

Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Halifax, Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

for
Multiple Myeloma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT06207799

Phase2, Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 22

Code: NCT04726241

Phase1, Phase2, Recruiting

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

for
Chronic Myelomonocytic Leukemia,
Location: Boston MA, Tampa FL, Rochester MN, Houston TX,
Sponsor: Solu Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06950034

Phase1, Recruiting

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

for
Hematopoietic Stem Cell Transplant, CAR-T Cell Therapy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT06575712

Recruiting

His-Bundle Corrective Pacing in Heart Failure

for
Right Bundle-Branch Block, Heart Failure, His-bundle Pacing,
Location: New York NY, Ridgewood NJ, Burlington VT,
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT05265520

Recruiting
New

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

for
Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma
Location: The Bronx NY, New York NY, Bel Air MD, Glen Burnie MD,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07452458

Phase3, Recruiting
New

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

for
Early Stage Lung Non-Small Cell Carcinoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT07718672

Phase2, Recruiting
New

Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing

for
Sickle Cell Disease
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 8 - 18

Code: NCT07562451

Recruiting
New

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

for
Stem Cell Transplantation, Myelodysplastic Syndromes,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT07469592

Recruiting
New

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

for
Pediatric Asthma, Acute Asthma, BiPAP,
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 5 - 17

Code: NCT07582211

Recruiting
New

Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)

for
Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM),
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07434791

Recruiting
New

Enhancing Diabetes Care by Treating Insomnia

for
Diabetes Type 2, Insomnia
Location: Zachary LA
Sponsor: Tulane University

Sex: All

Age: 40+

Code: NCT07062406

Recruiting
New

App-Based Certified Diabetes Education Therapy (AB-CDE)

for
Type 1 Diabetes (T1D)
Location: Boston MA, New York NY, Indianapolis IN, Aurora CO,
Sponsor: Oregon Health and Science University

Sex: All

Age: 18+

Code: NCT07282639

Recruiting
New

Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction

for
Patulous Eustachian Tube Dysfunction,
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT07796139

Recruiting