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Serial MRI Scans During Radiation Therapy

for
Glioblastoma, Esophageal Cancer, Radiotherapy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04188535

Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

for
Acute Ovarian Failure, Infertility,
Location: Bethesda MD
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: Female

Age: 4 - 35

Code: NCT05440617

Recruiting

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial

for
Bleeding Post Cardiac Surgery, Indication for Anticoagulation
Location: St. John's, Quebec, Montreal, Toronto, Hamilton,
Sponsor: Population Health Research Institute

Sex: All

Age: 18+

Code: NCT04284839

Phase3, Recruiting

Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02464696

Recruiting

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

for
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07250087

Phase1, Recruiting

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Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Jonathan Schoenfeld, MD, MPH

Sex: All

Age: 22+

Code: NCT04900623

Phase2, Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, Farmington CT, New Haven CT, New York NY,
Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All

Age: 18+

Code: NCT06667908

Phase2, Recruiting

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

for
High Grade Glioma, MGMT-Unmethylated Glioblastoma,
Location: Lake Success NY, Miami FL, San Diego CA, Los Angeles CA,
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06504381

Phase1, Phase2, Recruiting

Dynamic Connectivity Under Metabolic Constraints

for
Insulin Resistance, Healthy, Diet Modification, Aging
Location: Charlestown MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT04840095

Recruiting

The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy

for
COPD, Chronic Obstructive Pulmonary Disease
Location: Fort Wayne IN
Sponsor: Lutheran Hospital, Indiana

Sex: All

Age: 18+

Code: NCT03081650

Recruiting

Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC

for
Locally Advanced Skin Squamous Cell Carcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05085496

Phase1, Recruiting

Metabolism and Sleep Apnea Treatment

for
Obstructive Sleep Apnea, Fat Disorder
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18 - 70

Code: NCT05539716

Recruiting

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05541016

Phase2, Recruiting

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

for
Mesothelin Positive, Mesothelin-Expressing Tumors,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06623396

Phase1, Recruiting

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

for
B-ALL, DLBCL, B ALL, Dlbcl-Ci, DLBCL Unclassifiable,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04512716

Early_phase1, Recruiting

Hypoglycemia at Initiation of Pump Therapy in Children With Type 1 Diabetes

for
Type 1 Diabetes
Location: Montreal
Sponsor: St. Justine's Hospital

Sex: All

Age: 0 - 18

Code: NCT01840358

Recruiting

T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients

for
SARS-CoV-2 Infection
Location: Baltimore MD, Washington D.C. DC
Sponsor: Children's National Research Institute

Sex: All

Age: 2 - 70+

Code: NCT05141058

Phase1, Recruiting

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

for
Head and Neck Squamous Cell Carcinoma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05674396

Phase2, Recruiting

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for
Lung Non-Small Cell Carcinoma, Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05830058

Phase2, Recruiting

Enhanced Coordinated Specialty Care for Early Psychosis

for
Psychosis, Schizophrenia, Schizoaffective Disorder,
Location: Boston MA, Cambridge MA, Belmont MA, Worcester MA
Sponsor: Mclean Hospital

Sex: All

Age: 0+

Code: NCT06071858

Recruiting