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A Study to Train a Machine Learning Algorithm for an Evaluation of the Use of Biometric Data Captured at the Wrist for the Identification of Acute Opioid Use Events and the Quantification of Opioid Withdrawal in Opioid Dependent Individuals

for
Treatment for Opioid Use Disorder
Location: Wilmington NC, Austin TX, Cedar Park TX
Sponsor: OpiAID

Sex: All

Age: 22+

Code: NCT07405398

Recruiting

WellSpan-THRIVE Cancer QOL Study

for
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative,
Location: Ephrata PA, Lebanon PA, York PA, Gettysburg PA,
Sponsor: WellSpan Health

Sex: All

Age: 18+

Code: NCT07433660

Recruiting

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer

for
Relapsed/Refractory Small Cell Lung Cancer
Location: Durham NC, Cleveland OH, Detroit MI, Nashville TN
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07325136

Phase1, Phase2, Recruiting

TIL Therapy in cSCC and MCC

for
Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma,
Location: Boston MA
Sponsor: Karam Khaddour, MD, MS

Sex: All

Age: 18+

Code: NCT07288073

Phase2, Recruiting

Sensorimotor Training to Enhance Performance - the STEP AHEAD Program

for
Ice Hockey Players
Location: Calgary
Sponsor: Sport Injury Prevention Research Centre

Sex: All

Age: 12 - 40

Code: NCT07402746

Recruiting

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Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

for
Small Cell Lung Cancer ( SCLC ),
Location: Detroit MI
Sponsor: Bindu R Potugari

Sex: All

Age: 18+

Code: NCT07339059

Phase2, Recruiting

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

for
Sickle Cell Disease,
Location: Torrance CA
Sponsor: Mohsen Saidinejad

Sex: All

Age: 5 - 20

Code: NCT07369024

Phase2, Recruiting

Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

for
Human Papillomavirus-Negative Neck Squamous Cell Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06997094

Phase1, Recruiting

Beat the Heat Boston

for
Hot Weather; Adverse Effect, Heat Effect, Heat Stress,
Location: Boston MA
Sponsor: Harvard School of Public Health (HSPH)

Sex: All

Age: 55 - 70+

Code: NCT06982339

Recruiting

Robotic Exoskeletons in Acute Care Therapy

for
Patients Post-cardiothoracic Surgery
Location: Dallas TX
Sponsor: Baylor Research Institute

Sex: All

Age: 18+

Code: NCT07353892

Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for
Small-cell Lung Cancer
Location: New Haven CT, Stony Brook NY, The Bronx NY, Broomall PA,
Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All

Age: 18+

Code: NCT07218146

Phase3, Recruiting

Suzetrigine in Total Hip Arthroplasty

for
Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\),
Location: New York NY
Sponsor: Hospital for Special Surgery, New York

Sex: All

Age: 18 - 70+

Code: NCT07226700

Phase3, Recruiting

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Brewer ME, Stony Brook NY, Long Branch NJ,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07195734

Phase2, Recruiting

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

for
Esophageal Squamous Cell Carcinoma
Location: Pittsburgh PA
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06780111

Phase1, Phase2, Recruiting

Quadriceps Strengthening ACL Reconstruction

for
ACL Tear
Location: Sunnyvale CA
Sponsor: Stanford University

Sex: All

Age: 13 - 17

Code: NCT07015541

Recruiting

Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy

for
Obesity in Children, Bone Strength, GLP - 1,
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: All

Age: 12 - 21

Code: NCT06903923

Phase2, Recruiting

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

for
Cancer, Immunotherapy, Advanced Solid Tumors Cancer,
Location: Frederick MD, St Louis MO, Springfield MO,
Sponsor: Elephas

Sex: All

Age: 18+

Code: NCT07327489

Recruiting

CBTi for the Treatment of Insomnia in Type 1 Diabetes

for
Diabetes Mellitus Type 1, Insomnia
Location: Chicago IL
Sponsor: University of Illinois at Chicago

Sex: All

Age: 18 - 65

Code: NCT07091318

Early_phase1, Recruiting

Study of Epcoritamab as a Consolidation Therapy in CLL/SLL

for
CLL/SLL, CLL, SLL, Chronic Lymphocytic Leukemia,
Location: Cincinnati OH
Sponsor: Zulfa Omer

Sex: All

Age: 18+

Code: NCT07108998

Phase2, Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for
Type 2 Diabetes, Cortisol Excess
Location: Springfield MA, West Chester PA, Morehead City NC,
Sponsor: Sparrow Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07296484

Phase2, Recruiting