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A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

for
Head and Neck Cancer, Head and Neck Carcinoma,
Location: Commack NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05544136

Phase2, Recruiting

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

for
Head and Neck Cancer, Head Cancer, Head Cancer Neck,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT04722523

Phase1, Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for
Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma,
Location: New Haven CT, The Bronx NY, New York NY,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: All

Age: 18+

Code: NCT01042379

Phase2, Recruiting

NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer

for
Breast Cancer, Cancer of the Breast
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: Female

Age: 18+

Code: NCT05837455

Phase2, Recruiting

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

for
Adipocytic Neoplasm, Liposarcoma, Atypical Fibroxanthoma,
Location: Boston MA, Atlanta GA, Cincinnati OH, Chicago IL,
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 30

Code: NCT06239272

Phase1, Phase2, Recruiting

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Commack NY, Uniondale NY, Mineola NY, Harrison NY,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06500481

Phase3, Recruiting

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

for
Metastatic Breast Cancer, Stage IV Breast Cancer, Breast Cancer,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06678269

Phase1, Recruiting

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

for
HPV, Oropharynx Cancer, HPV-Related Carcinoma,
Location: Commack NY, Rockville Centre NY, East White Plains NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05307939

Phase2, Recruiting

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

for
Lung Carcinoma, Lung Non-Small Cell Carcinoma,
Location: Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT05802186

Recruiting

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: New York NY, Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT06518057

Phase2, Recruiting

Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: Female

Age: 18+

Code: NCT06534125

Recruiting

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

for
Viral Infection, Hematopoietic Stem Cell Transplantation (HSCT),
Location: Baltimore MD, Washington D.C. DC, Bethesda MD
Sponsor: Children's National Research Institute

Sex: All

Age: 0 - 70+

Code: NCT04691622

Phase1, Recruiting

Immersive Healing: The Therapeutic Potential of Virtual Reality

for
Phantom Limb Pain (PLP)
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06077227

Recruiting

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

for
Advanced Breast Carcinoma, Advanced Endometrial Carcinoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05092373

Phase1, Recruiting

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

for
Head and Neck Carcinoma of Unknown Primary,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04754321

Phase1, Recruiting

Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07407920

Phase2, Recruiting

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

for
Glioblastoma, Brain Cancer, Glioblastoma Multiforme,
Location: New York NY, Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT06991101

Phase2, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Bath ME, Portland ME, Scarborough ME, Sanford ME,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

for
Nonmelanoma Skin Cancer, Basal Cell Carcinoma,
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07241585

Recruiting

Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T)

for
Ataxia Telangiectasia
Location: Boston MA
Sponsor: Timothy Yu

Sex: All

Age: 0 - 17

Code: NCT07215416

Phase1, Phase2, Recruiting