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A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort

for
Duchenne Muscular Dystrophy
Location: Norfolk VA, St Louis MO, Little Rock AR,
Sponsor: Sarepta Therapeutics, Inc.

Sex: Male

Age: 2+

Code: NCT04626674

Phase1, Recruiting

Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Second Primary Malignancy

for
Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukaemia,
Location: Dallas TX, Salt Lake City UT
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 0+

Code: NCT06357754

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for
Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT03412877

Phase2, Recruiting

Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

for
High-risk Prostate Cancer, Prostate Cancer
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: Male

Age: 18+

Code: NCT03541928

Phase2, Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for
Neoplasms
Location: Boston MA, New Haven CT, New York NY, Hackensack NJ,
Sponsor: Celgene

Sex: All

Age: 0+

Code: NCT03435796

Phase2, Phase3, Recruiting

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Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort

for
Invasive Mammary Carcinoma, Metastatic Breast Cancer
Location: Birmingham AL, Nashville TN, Dallas TX
Sponsor: Sonya Reid

Sex: All

Age: 18+

Code: NCT05693766

Phase2, Recruiting
New

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Cardiotoxicity,
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07761910

Phase2, Recruiting
New

Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy

for
Accupuncture, Prostate Cancer, Hormone Therapy, Hot Flashes
Location: Lexington KY
Sponsor: University of Kentucky

Sex: All

Age: 18 - 70+

Code: NCT07594002

Recruiting
New

Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype

for
Multiple Myeloma, Triple Negative Breast Cancer,
Location: Boston MA
Sponsor: Andrew Hantel, MD

Sex: All

Age: 18+

Code: NCT07341867

Phase1, Recruiting

Combination Therapy in Cancers With Mutations in DNA Repair Genes

for
Metastatic Solid Tumor, BRCA1 Mutation, BRCA2 Mutation,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT05694715

Phase1, Recruiting

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

for
Leukemia, Hematopoetic Stem Cell Transplantation,
Location: Tucson AZ
Sponsor: University of Arizona

Sex: All

Age: 21 - 55

Code: NCT06643221

Early_phase1, Recruiting

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

for
Cancer, Malignancies Multiple, Malignant Solid Tumor,
Location: Halifax, Fredericton, Sherbrooke, Montreal, Ottawa,
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT04151342

Recruiting

Nutrition OUtReach In Systems of Healthcare

for
ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION,
Location: Fairway KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 8 - 70+

Code: NCT06802406

Recruiting

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

for
Traumatic Brain Injury, Insomnia, Depression,
Location: Bethesda MD, Fort Bragg NC, Eglin Air Force Base FL,
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT05663034

Recruiting

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

for
Myeloablative Allogeneic Hematopoietic Cell Transplantation,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT05335434

Recruiting

Patient-centered, Optimal Integration of Survivorship and Palliative Care

for
Stage IV Non-small Cell Lung Cancer, Targeted Therapy,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT04900935

Recruiting

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

for
Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 0+

Code: NCT06295965

Recruiting

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

for
Liver Metastases, Stereotactic Body Radiation Therapy,
Location: Madison WI
Sponsor: University of Wisconsin, Madison

Sex: All

Age: 18+

Code: NCT04020276

Recruiting

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

for
Cancer, Cancer Gene Mutation, PAN Gene Mutation,
Location: Jacksonville FL, Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06008392

Recruiting

Can Blood Flow Restriction Therapy Improve Strength and Cross-Sectional Area for Shoulder External Rotators Better Than Exercise Alone?

for
Can Blood Flow Restriction Therapy Augments Strength Gains in the Rotator Cuff,
Location: Newberg OR
Sponsor: George Fox University

Sex: All

Age: 18+

Code: NCT04596020

Recruiting