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Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease

for
Glioma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07025226

Early_phase1, Recruiting

Mapping of Electrical Properties in the Brain

for
Malignant Glioma
Location: Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06470711

Recruiting

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

for
Glioblastoma, IDH-Wildtype,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07301268

Phase2, Recruiting

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

for
Low Grade Glioma of Brain
Location: Durham NC
Sponsor: Katy Peters, MD, PhD

Sex: All

Age: 18+

Code: NCT05609994

Phase1, Recruiting

CUE-102 in Recurrent Glioblastoma

for
Recurrent Glioblastoma, Glioblastoma, Glioma, Malignant
Location: Boston MA
Sponsor: David Reardon, MD

Sex: All

Age: 18+

Code: NCT06917885

Phase1, Recruiting

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Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma

for
Progressive Glioblastoma, Recurrent Glioblastoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07076472

Early_phase1, Recruiting

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

for
Glioma, Glioma, Malignant, Recurrent Glioma
Location: Miami FL
Sponsor: Baptist Health South Florida

Sex: All

Age: 18+

Code: NCT06397560

Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for
Malignant Glioma
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 1 - 21

Code: NCT05099003

Phase1, Phase2, Recruiting

A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

for
Glioblastoma, Brain Tumor
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07003542

Phase2, Recruiting

FearLess in NeuroOncology

for
Primary Malignant Brain Tumor, Glioblastoma (GBM), Astrocytoma,
Location: Richmond VA
Sponsor: Virginia Commonwealth University

Sex: All

Age: 18+

Code: NCT06989086

Recruiting

ASCENT Intervention for Brain Tumor Patients

for
Malignant Brain Tumor, Glioma, Coping Skills,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06099743

Recruiting

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

for
Low-grade Glioma, Recurrent Low Grade Glioma,
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 2 - 25

Code: NCT07506239

Recruiting

UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-4

for
Glioblastoma (GBM), Astrocytoma, Grade IV
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: All

Age: 18+

Code: NCT07459101

Recruiting

D2C7-IT + 2141-V11 Combination Post-resection in rGBM

for
Recurrent Glioblastoma IDH Wildtype
Location: Durham NC
Sponsor: Darell Bigner

Sex: All

Age: 18+

Code: NCT06455605

Phase1, Recruiting

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

for
Glioblastoma, Anaplastic Astrocytoma
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT03603405

Phase1, Phase2, Recruiting

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

for
Brain Cancer, Glioblastoma, Metastatic Cancer,
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06058988

Phase2, Recruiting

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

for
Glioma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05489783

Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

for
Diffuse Intrinsic Pontine Glioma, High Grade Glioma,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 1 - 25

Code: NCT04099797

Phase1, Recruiting

Hyperpolarized Imaging in Diagnosing Participants With Glioma

for
Glioma
Location: San Francisco CA
Sponsor: Susan Chang

Sex: All

Age: 19+

Code: NCT03739411

Phase1, Recruiting

A Vaccine Trial for Low Grade Gliomas

for
Low Grade Glioma
Location: Pittsburgh PA
Sponsor: James Felker

Sex: All

Age: 1 - 21

Code: NCT02358187

Phase2, Recruiting