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ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma

for
Glioblastoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05917145

Phase1, Recruiting

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

for
Diffuse Glioma, Malignant Glioma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05717153

Early_phase1, Recruiting

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

for
Malignant Glioma
Location: Jacksonville FL, Phoenix AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT05030298

Phase1, Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

for
Glioblastoma, Brain Cancer, Brain Neoplasm, Brain Tumor,
Location: New York NY
Sponsor: Northwell Health

Sex: All

Age: 18+

Code: NCT02861898

Phase1, Phase2, Recruiting

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for
Glioblastoma (GBM)
Location: Boston MA, New York NY, Summit NJ, New Brunswick NJ,
Sponsor: Diakonos Oncology Corporation

Sex: All

Age: 18+

Code: NCT06805305

Phase2, Recruiting

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Evaluation of the CONVIVO System

for
Glioblastoma, Glial Tumor, Brain Metastases, Meningioma,
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT05139277

Recruiting

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

for
Glioma, Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 0+

Code: NCT01772771

Recruiting

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

for
High-grade Glioma, Medulloblastoma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 2 - 25

Code: NCT06624371

Phase1, Recruiting

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

for
Glioma
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18 - 70+

Code: NCT04772456

Phase1, Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for
Low Grade Astrocytoma, Low Grade Glioma,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 2 - 21

Code: NCT04166409

Phase3, Recruiting

Implantable Microdevice In Primary Brain Tumors

for
Grade II Glioma, Grade III Glioma, Grade IV Glioma, Astrocytoma,
Location: Boston MA
Sponsor: Oliver Jonas

Sex: All

Age: 18+

Code: NCT04135807

Early_phase1, Recruiting

Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors

for
Malignant Brain Glioma
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 0 - 21

Code: NCT04908709

Recruiting

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

for
Recurrent World Health Organization (WHO) Grade II Glioma,
Location: San Francisco CA
Sponsor: Susan Chang

Sex: All

Age: 18+

Code: NCT04540107

Phase1, Recruiting

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

for
Glioma
Location: San Antonio TX
Sponsor: Plus Therapeutics

Sex: All

Age: 18+

Code: NCT05460507

Phase1, Recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

for
Low Grade Glioma, Malignant Brain Glioma,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06132685

Phase2, Recruiting

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

for
Recurrent Malignant Glioma, Recurrent WHO Grade 3 Glioma,
Location: Columbus OH
Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06964737

Phase1, Recruiting

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

for
Low Grade Glioma, High Grade Glioma
Location: Chicago IL
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All

Age: 1 - 26

Code: NCT06712875

Phase1, Phase2, Recruiting

MCT for the Harvard/UCSF ROBIN Center

for
Glioma, Childhood Brainstem, Neuroblastoma
Location: Boston MA, San Francisco CA
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 0+

Code: NCT06000787

Recruiting

Registering Genomics and Imaging of Tumors (ReGIT)

for
Glioma
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT05386043

Recruiting

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

for
Recurrent Gliosarcoma, Recurrent Supratentorial Glioblastoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT04991870

Phase1, Recruiting