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Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for
Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma,
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07628634

Early_phase1, Recruiting

A Study of Mirdametinib in People With Central Nervous System Tumors

for
Central Nervous System Tumors, Glioma
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07539441

Phase1, Phase2, Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for
Atypical Teratoid/Rhabdoid Tumor,
Location: Hartford CT, Hackensack NJ, Hershey PA, Miami FL,
Sponsor: Milton S. Hershey Medical Center

Sex: All

Age: 0 - 26

Code: NCT06465199

Phase1, Phase2, Recruiting

Chronic CED of TPT for Recurrent Malignant Glioma

for
Brain Tumor, Recurrent, Malignant Glioma (WHO Grade III or IV),
Location: New York NY
Sponsor: Jeffrey N. Bruce

Sex: All

Age: 18+

Code: NCT06666712

Phase1, Recruiting

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

for
Brain Cancer, Brain Tumor, Brain Neoplasms, Primary Brain Tumor,
Location: Lebanon NH
Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All

Age: 18+

Code: NCT06930846

Recruiting

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ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

for
Diffuse Intrinsic Pontine Gliomas (DIPG), Progressive DIPG,
Location: Washington D.C. DC, Toronto, Columbus OH, Ann Arbor MI,
Sponsor: Nationwide Children's Hospital

Sex: All

Age: 1 - 39

Code: NCT06838676

Phase2, Recruiting

Imaging of Solid Tumors Using 18F-TRX

for
Solid Tumor, Solid Carcinoma,
Location: San Francisco CA
Sponsor: Rahul Aggarwal

Sex: All

Age: 18+

Code: NCT06942104

Phase1, Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for
Oncology, MEK Mutation, RAF Gene Mutation,
Location: New York NY, Fairfax VA, Buffalo NY, Pittsburgh PA,
Sponsor: Nested Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06326411

Phase1, Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

for
Primary Brain Tumor, Glioma, Meningioma, Schwannoma
Location: San Diego CA
Sponsor: Jona Hattangadi-Gluth

Sex: All

Age: 18 - 70+

Code: NCT05576103

Recruiting

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

for
Glioblastoma Multiforme, Anaplastic Astrocytoma,
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 1 - 21

Code: NCT05956821

Phase1, Phase2, Recruiting

Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells

for
Glioblastoma Multiforme, Glycolytic Index,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06059690

Phase1, Phase2, Recruiting

Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

for
Glioblastoma Multiforme
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT05366179

Phase1, Recruiting

Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components

for
Glioma
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT00813787

Recruiting

Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma

for
Recurrent Glioblastoma
Location: Miami FL
Sponsor: University of Miami

Sex: All

Age: 18+

Code: NCT05284643

Recruiting

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

for
Diffuse Intrinsic Pontine Glioma,
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT03101813

Recruiting

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

for
Malignant Brain Neoplasm, Malignant Glioma
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 18+

Code: NCT03510208

Phase1, Phase2, Recruiting

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

for
Glioma, Malignant Brain Neoplasm, Meningioma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06650163

Phase1, Recruiting

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

for
Brain Cancer, Glioma
Location: New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT00870129

Recruiting

BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors

for
Glioblastoma (GBM)
Location: Phoenix AZ
Sponsor: Nader Sanai

Sex: All

Age: 18+

Code: NCT07485049

Early_phase1, Recruiting

A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases

for
Glioblastoma (GBM), Brain Metastasases
Location: Phoenix AZ
Sponsor: Nader Sanai

Sex: All

Age: 18+

Code: NCT07268053

Early_phase1, Recruiting