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ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

for
ADNP, Helsmoortel-Van Der Aa Syndrome, Autism Spectrum Disorder
Location: New York NY
Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All

Age: 2+

Code: NCT03718936

Recruiting

Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

for
Hereditary Angioedema (HAE)
Location: Montreal, Hershey PA, Birmingham AL, Milwaukee WI,
Sponsor: Pharvaris Netherlands B.V.

Sex: All

Age: 12+

Code: NCT06679881

Phase3, Recruiting

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

for
Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis,
Location: Philadelphia PA, Charlottesville VA, Toronto, Hamilton
Sponsor: Peter Merkel

Sex: All

Age: 5+

Code: NCT03004326

Recruiting

Lanadelumab in Long-term Prophylaxis of Acquired Angioedema

for
Angioedema
Location: Cincinnati OH
Sponsor: Bernstein Clinical Research Center

Sex: All

Age: 18+

Code: NCT06818474

Recruiting

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for
Chronic Inducible Urticaria, Cold Urticaria,
Location: New York NY, Baltimore MD, Hialeah FL, Miami Lakes FL,
Sponsor: Celldex Therapeutics

Sex: All

Age: 18+

Code: NCT07266402

Phase3, Recruiting

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Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

for
Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)
Location: Hershey PA, St Louis MO, Edmonton, San Diego CA,
Sponsor: Pharvaris Netherlands B.V.

Sex: All

Age: 18+

Code: NCT07266805

Phase3, Recruiting

A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)

for
Hereditary Angioedemas
Location: Belleville NJ, Miami FL, Saint Charles IL, Phoenix AZ,
Sponsor: CSL Behring

Sex: All

Age: 12+

Code: NCT07001280

Recruiting

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

for
Chronic Spontaneous Urticaria
Location: Quebec, White Marsh MD, Ottawa, Niagara Falls,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07219615

Phase2, Recruiting

An Outpatient Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous Urticaria

for
Urticaria Chronic
Location: Cincinnati OH, Glenview IL
Sponsor: ARS Pharmaceuticals, Inc.

Sex: All

Age: 18 - 65

Code: NCT06927999

Phase2, Recruiting

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

for
Chronic Spontaneous Urticaria (CSU)
Location: Boston MA, Farmington CT, The Bronx NY,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06868212

Phase3, Recruiting

Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria

for
Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU),
Location: North Miami Beach FL, Glenview IL
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06865651

Phase2, Recruiting

The Myelin Disorders Biorepository Project

for
Leukodystrophy, White Matter Disease, Leukoencephalopathies,
Location: Boston MA, Philadelphia PA, Baltimore MD,
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0+

Code: NCT03047369

Recruiting

Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers

for
Healthy Volunteer
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 65

Code: NCT03878121

Phase1, Recruiting

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

for
Economic Hardship, Condomless Sex, Utilization, Health Care
Location: Baltimore MD
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 24

Code: NCT06096324

Recruiting

The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to Care

for
Syphilis
Location: Hamilton
Sponsor: McMaster University

Sex: All

Age: 13 - 49

Code: NCT06829602

Recruiting

Forging Sustainable Solutions for HIV Continuity of Care Through Medical-legal Partnerships

for
Organizational Partnerships for Healthy Living,
Location: Philadelphia PA
Sponsor: Temple University

Sex: All

Age: 18 - 70+

Code: NCT05912842

Phase1, Recruiting

HIV Medication Adherence in Underserved Populations

for
Human Immunodeficiency Virus,
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18 - 70+

Code: NCT02392884

Recruiting

Body Image and Self-Care in HIV-Infected MSM

for
Body Image Disturbance, Medication Adherence
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: Male

Age: 18 - 65

Code: NCT01817621

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

for
Diffuse Large Cell Lymphoma, Non-Hodgkin Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05389423

Phase1, Recruiting

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

for
Herpes Zoster
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18+

Code: NCT05580458

Phase1, Phase2, Recruiting