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Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

for
Indolent Lymphomas, Lymphoma, Chronic Lymphocytic Leukemia,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06860880

Recruiting

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: St. John's, Boston MA, Norwich CT, New Haven CT, Quebec,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06943872

Phase3, Recruiting

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

for
Recurrent Transformed Chronic Lymphocytic Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06735664

Phase1, Recruiting

Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL)

for
Leukemia, Relapsed Leukemia, Chronic Lymphocytic Leukemia,
Location: Boston MA
Sponsor: Jennifer R. Brown, MD, PhD

Sex: All

Age: 18+

Code: NCT06644183

Phase1, Phase2, Recruiting

LP-168 and Obinutuzumab for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This

for
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,
Location: Cincinnati OH
Sponsor: Zulfa Omer

Sex: All

Age: 18+

Code: NCT06978088

Phase2, Recruiting

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Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

for
Small Lymphocytic Lymphoma (SLL),
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07030400

Recruiting

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

for
Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06839053

Phase2, Recruiting

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Boston MA, Hampton VA, Greenville NC, York PA,
Sponsor: Loxo Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06588478

Phase2, Recruiting

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

for
Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC)
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT04844528

Phase2, Recruiting

Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05183854

Phase2, Recruiting

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

for
CLL/SLL, Waldenstrom Macroglobulinemia, Follicular Lymphoma,
Location: Durham NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 18+

Code: NCT04775745

Phase1, Recruiting

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Saint John, Damariscotta ME, Brunswick ME, Augusta ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04269902

Phase3, Recruiting

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

for
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06784167

Recruiting

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

for
Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 70+

Code: NCT01853631

Phase1, Recruiting

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

for
Waldenstrom Macroglobulinemia, Lymphoplasmacytic Lymphoma,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT00923507

Recruiting
New

Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

for
Non Hodgkin Lymphoma, B-cell Non Hodgkin Lymphoma,
Location: Cleveland OH
Sponsor: Paolo Caimi, MD

Sex: All

Age: 18+

Code: NCT07225439

Phase1, Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

for
B-cell Lymphoma, Non-Hodgkin Lymphoma, B-cell Malignancy,
Location: St Louis MO, Westwood KS, San Antonio TX,
Sponsor: CRISPR Therapeutics AG

Sex: All

Age: 18+

Code: NCT05643742

Phase1, Phase2, Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

for
Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL,
Location: Boston MA, Providence RI, The Bronx NY, New York NY,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT05544019

Phase1, Recruiting

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

for
Relapsed or Refractory CD19+ B-cell Lymphoma,
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05963217

Phase1, Recruiting

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for
B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma,
Location: Valhalla NY, Chapel Hill NC, Jacksonville FL,
Sponsor: Vironexis Biotherapeutics Inc.

Sex: All

Age: 13 - 70+

Code: NCT06533579

Phase1, Phase2, Recruiting