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PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies

for
Follicular Lymphoma,
Location: Louisville KY
Sponsor: Qilu Puget Sound Biotherapeutics (dba Sound Biologics)

Sex: All

Age: 18+

Code: NCT05003141

Phase1, Recruiting

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

for
Non Hodgkin Lymphoma (NHL), Mantle Cell Lymphoma (MCL),
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18 - 70+

Code: NCT04186520

Phase1, Phase2, Recruiting

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

for
B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma,
Location: Boston MA, Quebec, New York NY, Bethesda MD,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT05006716

Phase1, Phase2, Recruiting

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

for
Acute Leukemia, Acute Myeloid Leukemia,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 0 - 60

Code: NCT03314974

Phase2, Recruiting

Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

for
Diffuse Large B Cell Lymphoma, Chronic Lymphocytic Leukemia,
Location: Columbus OH, Cincinnati OH, Goshen IN, Dallas TX
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04502394

Phase1, Phase2, Recruiting

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Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for
Recurrent Diffuse Large B-Cell Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05672251

Phase2, Recruiting

A Study of APG-3288 in Relapsed/Refractory Blood Cancers

for
Relapsed/Refractory Hematological Malignancies,
Location: East Brunswick NJ, Grand Rapids MI, Los Angeles CA
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT07424833

Phase1, Recruiting

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

for
Richter Syndrome, Diffuse Large B-Cell Lymphoma,
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: All

Age: 18+

Code: NCT06863402

Phase2, Recruiting

Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL

for
B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05702853

Phase1, Phase2, Recruiting

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04892277

Phase1, Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

for
B-Cell Non-Hodgkin Lymphoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06191887

Phase1, Recruiting

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

for
B-Cell Lymphoma, B Acute Lymphoblastic Leukemia,
Location: Pittsburgh PA
Sponsor: John Lister

Sex: All

Age: 18 - 70+

Code: NCT05281809

Phase2, Recruiting

Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies

for
NHL, Relapsed, Adult, B-cell Lymphoma, B-cell Leukemia,
Location: Houston TX, Portland OR, San Francisco CA
Sponsor: Athenex, Inc.

Sex: All

Age: 3 - 70+

Code: NCT05487651

Phase1, Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

for
B-NHL, B-Non Hodgkin Lymphoma, Acute Lymphocytic Leukemia,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 3 - 39

Code: NCT05442515

Phase1, Phase2, Recruiting

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, Buffalo NY, Chicago IL
Sponsor: Marlise Luskin, MD

Sex: All

Age: 18+

Code: NCT03595917

Phase1, Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 0 - 39

Code: NCT05800210

Phase2, Recruiting

A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab

for
B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia,
Location: Little Rock AR, Springdale AR
Sponsor: Arkansas Children's Hospital Research Institute

Sex: All

Age: 1 - 23

Code: NCT07422337

Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for
Hematologic Malignancy, Leukemia, Lymphoma,
Location: Cincinnati OH, Milwaukee WI, Houston TX, Aurora CO
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0 - 38

Code: NCT06131801

Recruiting

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

for
Leukemia, Myeloid, Chronic, Myeloid Leukemia,
Location: Baltimore MD, Toronto, Augusta GA, Cleveland OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18+

Code: NCT04260022

Phase1, Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

for
Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT03589729

Phase2, Recruiting