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Asciminib Roll-over Study

for
Chronic Myelogenous Leukemia,
Location: New York NY, Montreal, Ann Arbor MI, Milwaukee WI,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 7 - 70+

Code: NCT04877522

Recruiting

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

for
Leukemia, Acute Myeloid Leukemia in Remission, Myelodysplasia,
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 0 - 25

Code: NCT05794880

Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

for
Large B-Cell Lymphoma With IRF4 Rearrangement,
Location: Jacksonville FL, La Crosse WI, Eau Claire WI,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06834373

Phase2, Recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

for
Clonal Cytopenia of Undetermined Significance,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03418038

Phase2, Recruiting

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Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

for
Refractory Non-Hodgkin Lymphoma, Burkitt Lymphoma,
Location: San Francisco CA
Sponsor: C. Babis Andreadis

Sex: All

Age: 18+

Code: NCT04545762

Phase1, Recruiting

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

for
Monoclonal Gammopathy of Undetermined Significance (MGUS),
Location: Weymouth MA, Boston MA, Brighton MA, Methuen MA,
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT02269592

Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

for
B-Cell Lymphoma, Myelodysplastic Syndromes (MDS),
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 70+

Code: NCT05092451

Phase1, Phase2, Recruiting
Featured

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia (CLL)
Location: Boston MA, Hackensack NJ, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT04895436

Phase2, Recruiting
Featured

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia
Location: Providence RI, Worcester MA, New Haven CT, New York NY,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06428019

Phase3, Recruiting

Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

for
Richter Syndrome, Chronic Lymphocytic Leukemia
Location: New York NY, Columbus OH
Sponsor: Weill Medical College of Cornell University

Sex: All

Age: 18+

Code: NCT04679012

Phase2, Recruiting

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

for
Relapsed CLL, Refractory CLL, Refractory Lymphoma
Location: Cleveland OH
Sponsor: Paolo Caimi, MD

Sex: All

Age: 18+

Code: NCT06916767

Phase1, Recruiting

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for
Non-Hodgkin Lymphoma, B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, Providence RI, New York NY, Baltimore MD,
Sponsor: Imugene Limited

Sex: All

Age: 18+

Code: NCT03666000

Phase1, Recruiting

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

for
Mantle Cell Lymphoma, Follicular Lymphoma,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04223765

Phase1, Recruiting